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The possibility of positron emission tomography (PET) as a predictive tool for preoperative evaluation of second implant in bilateral cochlear implant patients

Research Project

Project/Area Number 24592554
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Otorhinolaryngology
Research InstitutionUniversity of Miyazaki

Principal Investigator

Tono Tetsuya  宮崎大学, 医学部, 教授 (80145424)

Co-Investigator(Kenkyū-buntansha) USHISAKO YASUAKI  宮崎大学, 医学部, 助教 (10185001)
NAGAMACHI SHIGEKI  宮崎大学, 医学部, 准教授 (40180517)
NAGANO YUKI  宮崎大学, 医学部, 助教 (50404405)
OKUDA TAKUMI  宮崎大学, 医学部, 助教 (60404456)
FUKUDOME SHINJI  宮崎大学, 医学部, 助教 (80404458)
TAKASHI GOTO  宮崎大学, 医学部, 助教 (20600612)
NAKASHIMA TAKAHIRO  宮崎大学, 医学部, 助教 (90315375)
Project Period (FY) 2012-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Keywords後迷路機能評価 / 人工内耳 / 高度感音難聴 / PET-CT / 電気蝸牛刺激検査
Outline of Final Research Achievements

The purpose of this study is to evaluate the efficacy of positron emission tomography (PET) as a tool of preoperative examination which predicts the usefulness of second implant in bilateral cochlear implant (CI) user. Seventeen patients with bilateral profound sensorineural hearing loss were examined. Glucose metabolism of the brain was measured with PET/CT after and before electrical auditory stimulation. Correlation between the postoperative results and primary auditory cortex activation of patients who underwent unilateral CI was not observed. In the pediatric patients who underwent bilateral CI, Good postoperative hearing results of the second implant were exhibited in a case that had the primary auditory cortex activation. On the other hand, in case the primary auditory cortex activation was not recognized exhibited poor postoperative results. Preoperative evaluation using PET/CT is potentially useful as test to predict the effect of the second implant.

Report

(5 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (20 results)

All 2016 2015 2014 2013 2012

All Journal Article (8 results) (of which Peer Reviewed: 8 results,  Open Access: 7 results,  Acknowledgement Compliant: 3 results) Presentation (10 results) (of which Invited: 1 results) Book (2 results)

  • [Journal Article] Case Report of Atlantoaxial Rotatory Fixation after CochlearImplantation.(in press)2016

    • Author(s)
      Nakashima T, Matsuda K, Okuda T, Tono T, Takaki M, Hayashi T, Hanamure Y
    • Journal Title

      Case Reports in Otolaryngology.

      Volume: 2016

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Clinical features and treatment outcomes of otitis media with antieutrophil cytoplasmic antibody (ANCA)-associated vasculitis (OMAAV): a retrospective analysis of 235 patients from a nationwide survey in Japan.2016

    • Author(s)
      Harabuchi Y, Kishibe K, Tateyama K, Morita Y, Yoshida N, Kunimoto Y, Matusi T, Sakaguchi H, Okada M, Watanabe T, Inagaki A, Kobayashi S, Iino Y, Murakami S, Takahashi H, Tono T
    • Journal Title

      Modern Rheumatology

      Volume: Early Online Issue: 1 Pages: 1-7

    • DOI

      10.1080/14397595.2016.1177926

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Discrimination of Japanese monosyllables in patients with high-frequency hearing loss2016

    • Author(s)
      Karino S, Usami S, Kumakawa K, Takahashi H, Tono T, Naito Y, Doi K, Ito K, Suzuki M, Sakata H, Takumi Y, Iwasaki S, Kakigi A, Yamasoba T
    • Journal Title

      Auris Nasus Larynx

      Volume: 43 Issue: 3 Pages: 269

    • DOI

      10.1016/j.anl.2015.10.003

    • NAID

      130005330303

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] 伝音・混合性難聴に対するFMT正円窓留置によるVIBRANT SOUNDBRIDGEの効果.2016

    • Author(s)
      松田圭二,東野哲也,神崎 晶, 熊川孝三, 宇佐美真一, 岩崎 聡, 山中 昇, 土井勝美, 内藤 泰, 暁 清文, 高橋晴雄, 神田幸彦
    • Journal Title

      日本耳鼻咽喉科学会会報

      Volume: 119(1) Pages: 37-45

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Late Pneumolabyrinth May Be Induced by Old Penetrating Injury: Possibility of Undiagnosed Posttraumatic Perilymphatic Fistula.2015

    • Author(s)
      Takahiro Nakashima, Keiji Matsuda, Takumi Okuda, Tetsuya Tono, Minoru Takaki, Tamon Hayashi, Yutaka Hanamure
    • Journal Title

      Case Reports in Otolaryngol

      Volume: 2015 Pages: 1-4

    • DOI

      10.1155/2015/506484

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Hearing preservation and clinical outcome of 32 consecutive electric acoustic stimulation (EAS) surgeries.2014

    • Author(s)
      Usami S, Moteki H, Tsukada K, Miyagawa M, Nishio SY, Takumi Y, Iwasaki S, Kumakawa K, Naito Y, Takahashi H, Kanda Y, Tono T
    • Journal Title

      Acta Otolaryngol

      Volume: 134 Issue: 7 Pages: 717-727

    • DOI

      10.3109/00016489.2014.894254

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] A case of cochlear implantation in a patient with Epstein syndrome.2014

    • Author(s)
      Nabekura T, Nagano Y, Matsuda K, Tono T
    • Journal Title

      Auris Nasus Larynx

      Volume: Oct Issue: 2 Pages: 160-162

    • DOI

      10.1016/j.anl.2014.09.004

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Glucose Metabolism in the Primary Auditory Cortex of Postlingually Deaf Patients: An FDG-PET Study2013

    • Author(s)
      Takumi Okuda, Shigeki Nagamachi, Yasuaki Ushisako, Tetsuya Tono
    • Journal Title

      ORL

      Volume: 75 Pages: 342-349

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] 伝音・混合性難聴に対するFMT正円窓留置によるVIBRANT SOUNDBRIDGEの効果 疾患別の有効性について.2015

    • Author(s)
      松田圭二,東野哲也,神崎 昌,熊川孝三, 宇佐美真一, 岩崎 聡, 山中 昇, 土井勝美, 内藤 泰, 暁 清文, 高橋晴雄, 神田幸彦
    • Organizer
      第60回日本聴覚医学会総会・学術講演会
    • Place of Presentation
      京王プラザホテル(東京都新宿区)
    • Year and Date
      2015-10-21
    • Related Report
      2015 Annual Research Report
  • [Presentation] 我が国における人工内耳医療の変遷.2015

    • Author(s)
      東野 哲也
    • Organizer
      第60回日本音声言語医学会ポストコングレスセミナー
    • Place of Presentation
      ウインクあいち(愛知県名古屋市)
    • Year and Date
      2015-10-17
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 倉澤美智子,北島史織,東野哲也2015

    • Author(s)
      人工内耳術側決定における蝸牛電気聴覚検査(PST)の役割.
    • Organizer
      第60回日本音声言語医学会総会・学術講演会
    • Place of Presentation
      ウインクあいち(愛知県名古屋市)
    • Year and Date
      2015-10-15
    • Related Report
      2015 Annual Research Report
  • [Presentation] 当科で経験した残存聴力活用型人工内耳(EAS)の経過.2015

    • Author(s)
      中島崇博,山本麻代,近藤香菜子,白根美帆,倉澤美智子,松田悠佑,平原信哉,奥田匠,中西 悠,長井慎成,松田圭二,東野哲也
    • Organizer
      第30回九州連合地方部会学術講演会/第129回日耳鼻宮崎県地方部会総会・学術講演会
    • Place of Presentation
      ホテル熊本テルサ(熊本県熊本市)
    • Year and Date
      2015-07-11
    • Related Report
      2015 Annual Research Report
  • [Presentation] 混合・伝音難聴に対するVSB手術の術後長期成績.2015

    • Author(s)
      松田圭二, 中島崇博, 平原信哉, 梶原 啓, 山田悠祐, 東野哲也
    • Organizer
      第116回日本耳鼻咽喉科学会総会・学術講演会
    • Place of Presentation
      東京国際フォーラム(東京都千代田区)
    • Year and Date
      2015-05-20
    • Related Report
      2015 Annual Research Report
  • [Presentation] 人工内耳埋め込み術を行った先天性サイトメガロウィルス感染症児2例.2015

    • Author(s)
      池ノ上あゆみ,白根美帆,東野哲也
    • Organizer
      第10回日本小児耳鼻咽喉科学会・学術講演会
    • Place of Presentation
      軽井沢プリンスホテル(長野県北佐久郡)
    • Year and Date
      2015-05-08
    • Related Report
      2015 Annual Research Report
  • [Presentation] 小児人工内耳術後に生じた環軸椎回旋位固定の一例.2015

    • Author(s)
      中島崇博,奥田 匠,高木 実,林 多聞,花牟禮豊,東野哲也
    • Organizer
      第10回日本小児耳鼻咽喉科学会・学術講演会
    • Place of Presentation
      軽井沢プリンスホテル(長野県北佐久郡)
    • Year and Date
      2015-05-08
    • Related Report
      2015 Annual Research Report
  • [Presentation] 残存聴力活用型人工内耳(EAS:Electric Acoustic Stimulation)装用者の音楽聴取能に関する検討.2014

    • Author(s)
      近藤香菜子, 牛迫泰明, 山本麻代, 白根美帆, 倉澤美智子, 松田悠佑, 奥田 匠,東野哲也
    • Organizer
      第59回日本聴覚医学会総会・学術講演会
    • Place of Presentation
      山口県下関市
    • Year and Date
      2014-11-27 – 2014-11-28
    • Related Report
      2014 Research-status Report
  • [Presentation] 本邦における人工中耳(Vibrant Soundbridge)臨床治験-静寂下, 雑音下の語音聴取成績-.2014

    • Author(s)
      松田圭二,東野哲也,神崎 晶,熊川孝三,宇佐美真一,岩崎 聡,山中 昇,土井勝美,内藤 泰, 暁 清文,高橋晴雄
    • Organizer
      第115回日本耳鼻咽喉科学会総会・学術講演会
    • Place of Presentation
      福岡県福岡市
    • Year and Date
      2014-05-14 – 2014-05-17
    • Related Report
      2014 Research-status Report
  • [Presentation] Usher症候群症例における聴覚野および視覚野のPETによる評価2012

    • Author(s)
      奥田 匠,永野由起,牛迫泰明,木原あゆみ,東野哲也
    • Organizer
      第57回日本聴覚医学会総会・学術講演会
    • Place of Presentation
      京都府
    • Related Report
      2012 Research-status Report
  • [Book] 今日の治療指針―私はこうしている―.2015

    • Author(s)
      東野 哲也
    • Publisher
      医学書院
    • Related Report
      2014 Research-status Report
  • [Book] ENTコンパス2014

    • Author(s)
      東野 哲也
    • Publisher
      ライフサイエンス
    • Related Report
      2014 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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