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Utility evaluation of phakic intraocular lens with a hole determined with anterior segment optical coherence tomography.

Research Project

Project/Area Number 24592642
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Ophthalmology
Research InstitutionKitasato University

Principal Investigator

KAMIYA KAZUTAKA  北里大学, 医学部, 准教授 (80439116)

Co-Investigator(Kenkyū-buntansha) SHIMIZU Kimiya  北里大学, 医学部, 教授 (60124674)
Co-Investigator(Renkei-kenkyūsha) IGARASHI Akihito  北里大学, 医学部, 助教 (50596434)
SHIRATANI Tetsu  北里大学, 医学部, 助教 (40525317)
KAWAMORITA Takushi  北里大学, 医療衛生学部, 講師 (80511899)
UOZATO Hiroshi  北里大学, 医療衛生学部, 前教授 (00118019)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2014: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords貫通孔付き有水晶体眼内レンズ / 長深度光干渉断層計 / 屈折矯正手術 / 安全性 / 白内障 / 有水晶体眼内レンズ / Hole ICL / 視機能 / 眼球光学特性 / 長期臨床成績 / 国際情報交換
Outline of Final Research Achievements

It was possible to optimize the size of Hole ICL by directly measuring the sulcus-to-sulcus diameter with swept source optical coherence tomography. There were no significant differences in the induction of higher-order aberrations, contrast sensitivity function, subjective and objective forward scattering, modulation transfer function, or glare and halo. Visual performance after Hole ICL implantation was superior to that after LASIK. A slight edge glare was detected by photography from the model of the Hole ICL-implanted eye, and it was prominent when dislocated or tilted. The speed of the aqueous flow was higher after Hole ICL implantation than that after conventional ICL implantation. Hole ICL implantation was safe and effective, and provided predictable and stable results, during the long-term follow-up period. The rates of cataract formation and the intraocular pressure rise were significantly lower after Hole ICL implantation than that after conventional ICL implantation.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (47 results)

All 2015 2014 2013 2012 Other

All Journal Article (22 results) (of which Peer Reviewed: 14 results) Presentation (25 results) (of which Invited: 12 results)

  • [Journal Article] Three-year follow-up of posterior chamber toric phakic intraocular lens implantation for the correction of high myopic astigmatism in eyes with keratoconus.2015

    • Author(s)
      Kamiya K, Shimizu K, Kobashi H, Igarashi A, Komatsu M, Nakamura A, Kojima T,
    • Journal Title

      Br J Ophthalmol.

      Volume: 99 Issue: 2 Pages: 177-83

    • DOI

      10.1136/bjophthalmol-2014-305612

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 貫通孔付き有水晶体眼内レンズ(Hole ICL)2015

    • Author(s)
      神谷 和孝
    • Journal Title

      眼科手術

      Volume: 28 Pages: 66-71

    • Related Report
      2014 Annual Research Report
  • [Journal Article] 貫通孔付き有水晶体眼内レンズ(Hole ICL)2015

    • Author(s)
      神谷 和孝
    • Journal Title

      あたらしい眼科

      Volume: 32 Pages: 243-4

    • Related Report
      2014 Annual Research Report
  • [Journal Article] Long-term quality of life after posterior chamber phakic intraocular lens implantation and after wavefront-guided laser in situ keratomileusis for myopia.2014

    • Author(s)
      Kobashi H, Kamiya K, Igarashi A, Matsumura K, Komatsu M, Shimizu K.
    • Journal Title

      J Cataract Refract Surg.

      Volume: 40 Issue: 12 Pages: 2019-24

    • DOI

      10.1016/j.jcrs.2014.03.028

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Clinical Evaluation of Corneal Biomechanical Parameters after Posterior Chamber Phakic Intraocular Lens Implantation.2014

    • Author(s)
      Ali M, Kamiya K, Shimizu K, Igarashi A, Ishii R.
    • Journal Title

      Cornea.

      Volume: 33 Issue: 5 Pages: 470-4

    • DOI

      10.1097/ico.0000000000000088

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Factors Influencing Long-term Regression after Posterior Chamber Phakic Intraocular Lens Implantation for Moderate to High Myopia.2014

    • Author(s)
      Kamiya K, Shimizu K, Igarashi A, Kobashi H.
    • Journal Title

      Am J Ophthalmol

      Volume: E-pub Mar 31 Issue: 1 Pages: 179-184.e1

    • DOI

      10.1016/j.ajo.2014.03.010

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Comparison of Optical Quality and Intraocular Scattering after Posterior Chamber Phakic Intraocular Lens with and without a Central Hole (Hole ICL and Conventional ICL) Implantation Using the Double-Pass Instrument.2013

    • Author(s)
      Kamiya K, Shimizu K, Saito A, Igarashi A, Kobashi H.
    • Journal Title

      PLoS ONE.

      Volume: 8 Issue: 6 Pages: e66846-e66846

    • DOI

      10.1371/journal.pone.0066846

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Visual performance after posterior chamber phakic intraocular lens implantation for myopia2013

    • Author(s)
      Kamiya K
    • Journal Title

      Expert Rev Ophthalmol.

      Volume: 7 Issue: 4 Pages: 299-301

    • DOI

      10.1586/eop.12.37

    • Related Report
      2013 Research-status Report
  • [Journal Article] Three-year follow-up of posterior chamber toric phakic intraocular lens implantation for moderate to high myopic astigmatism.2013

    • Author(s)
      Kamiya K, Shimizu K, Kobashi H, Igarashi A, Komatsu M.
    • Journal Title

      PLoS ONE.

      Volume: 8

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Eight-Year Follow-Up of Posterior Chamber Phakic Intraocular Lens Implantation for Moderate to High Myopia2013

    • Author(s)
      Igarashi A, Shimizu K, Kamiya K.
    • Journal Title

      Am J Ophthalmol

      Volume: 157 Pages: 532-539

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] 貫通孔付き有水晶体眼内レンズ(Hole ICL)2013

    • Author(s)
      神谷和孝
    • Journal Title

      IOL&RS

      Volume: 27 Pages: 335-339

    • Related Report
      2013 Research-status Report
  • [Journal Article] Intraindividual Comparison of Visual Performance after Posterior Chamber Phakic Intraocular Lens with and without a Central Hole Implantation for Moderate to High Myopia.2012

    • Author(s)
      Shimizu K, Kamiya K, Igarashi A, Shiratani T.
    • Journal Title

      Am J Ophthalmol

      Volume: 154 Pages: 486-494

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Clinical evaluation of optical quality and intraocular scattering after posterior chamber phakic intraocular lens implantation.2012

    • Author(s)
      Kamiya K, Shimizu K, Igarashi A, Kobashi H, Ishii R, Sato N.
    • Journal Title

      Invest Ophthalmol Vis Sci.

      Volume: 53 Pages: 3161-3166

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] トーリック有水晶体眼内レンズ2012

    • Author(s)
      神谷和孝
    • Journal Title

      あたらしい眼科

      Volume: 29 Pages: 497-498

    • Related Report
      2012 Research-status Report
  • [Journal Article] 中高齢者における近視矯正手術2012

    • Author(s)
      神谷和孝、五十嵐章史
    • Journal Title

      IOL&RS

      Volume: 26 Pages: 167-170

    • NAID

      10030791322

    • Related Report
      2012 Research-status Report
  • [Journal Article] 手術器具 Optical Quality Analysis System II2012

    • Author(s)
      神谷和孝
    • Journal Title

      IOL&RS

      Volume: 26 Pages: 210-213

    • Related Report
      2012 Research-status Report
  • [Journal Article] Early Clinical Outcomes of Posterior Chamber Phakic Intraocular Lens with a Central Hole (Hole ICL) Implantation for Moderate to High Myopia2012

    • Author(s)
      Shimizu K, Kamiya K, Igarashi A, Shiratani T.
    • Journal Title

      Br J Ophthalmol.

      Volume: 96 Pages: 267-270

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Long-term safety outcomes of posterior chamber phakic intraocular lens implantation for high myopia2012

    • Author(s)
      Miyuki Kitahara、Kazutaka Kamiya、Akihito Igarashi、Kimiya Shimizu
    • Journal Title

      The Kitasato Medical Journal

      Volume: 42 Pages: 111-119

    • NAID

      40019429435

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] 前眼部形状解析装置TMS-5による角膜径(white to white)測定の再現性と他機種との比較検討2012

    • Author(s)
      藤原和子、藤村芙佐子、神谷和孝、清水公也
    • Journal Title

      臨床眼科

      Volume: 66 Pages: 1411-1417

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Successful toric intraocular lens implantation in a patient with induced cataract and astigmatism after posterior chamber toric phakic intraocular lens implantation: a case report2012

    • Author(s)
      Kamiya K, Nakamura A, Miyake H, Nishimoto H, Shimizu K.
    • Journal Title

      J Med Case Rep.

      Volume: 6 Pages: 109-109

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Visual performance after posterior chamber phakic intraocular lens implantation for myopia2012

    • Author(s)
      Kamiya K,
    • Journal Title

      Expert Rev Ophthalmol.

      Volume: 7 Pages: 299-301

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] 円錐角膜に対する有水晶体眼内レンズ2012

    • Author(s)
      神谷和孝
    • Journal Title

      眼科手術

      Volume: 25 Pages: 497-501

    • NAID

      10031162320

    • Related Report
      2012 Research-status Report
  • [Presentation] 貫通孔付き有水晶体眼内レンズ(Hole ICL)2015

    • Author(s)
      神谷 和孝
    • Organizer
      第8回東京眼科アカデミー
    • Place of Presentation
      キャピトル ホテル東急(東京都千代田区)
    • Year and Date
      2015-02-08
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 執刀医からのリクエスト『術前の検査はここが大事』2015

    • Author(s)
      神谷 和孝
    • Organizer
      日本眼科手術学会学術総会
    • Place of Presentation
      京都国際会館(京都府京都市)
    • Year and Date
      2015-02-01
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 貫通孔付き有水晶体眼内レンズをマスターしよう2014

    • Author(s)
      神谷 和孝、清水 公也、市川 一夫、中村 友昭、北澤世志博
    • Organizer
      第68回日本臨床眼科学会
    • Place of Presentation
      神戸ポートピアホテル(兵庫県神戸市)
    • Year and Date
      2014-11-15
    • Related Report
      2014 Annual Research Report
  • [Presentation] 貫通孔付き有水晶体眼内レンズ2014

    • Author(s)
      神谷 和孝
    • Organizer
      第12回Bay Ophthalmic Surgical Seminar
    • Place of Presentation
      横浜シンポジア(神奈川県横浜市)
    • Year and Date
      2014-11-01
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 次世代の屈折矯正手術 ReLEx・Hole ICL2014

    • Author(s)
      神谷 和孝
    • Organizer
      角膜スキルアップセミナー
    • Place of Presentation
      三井ガーデンホテル広島(広島県広島市)
    • Year and Date
      2014-05-17
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Indications for and Designs of Toric IOLs2014

    • Author(s)
      Kazutaka Kamiya
    • Organizer
      WOC2014/APAO2014/118thJOS
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-04-02
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Four-Year Follow-Up of Hole ICL implantation2013

    • Author(s)
      Shimizu K, Kamiya K, Igarashi A
    • Organizer
      ASCRS•ASOA Symposium & Congress
    • Place of Presentation
      ASCRS San Francisco
    • Related Report
      2012 Research-status Report
  • [Presentation] トーリック有水晶体眼内レンズ2013

    • Author(s)
      神谷和孝
    • Organizer
      第36回日本眼科手術学会総会
    • Place of Presentation
      福岡
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] 有水晶体眼内レンズとlaser in situ keratomileusis術後の自覚症状の定量的検討2013

    • Author(s)
      小橋英長、神谷和孝、五十嵐章史、松村一弘、小松真理、清水公也
    • Organizer
      第36回日本眼科手術学会総会
    • Place of Presentation
      福岡
    • Related Report
      2012 Research-status Report
  • [Presentation] Visual Performance After Phakic Intraocular Lens Implantation2012

    • Author(s)
      Kamiya K
    • Organizer
      The 27th Asia Pacific Academy of Ophthalmology Congress
    • Place of Presentation
      Pusan, Korea
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] 有水晶体眼内レンズおよびLASIK術後屈折ずれが裸眼視力に及ぼす影響の基礎的・臨床的検討2012

    • Author(s)
      神谷和孝1、五十嵐章史1、清水公也1、小橋英長2、小松真理2、川守田拓志3、魚里博3(1北里大、2山王病院、3北里大・医療衛生)
    • Organizer
      第27回JSCRS学術総会
    • Place of Presentation
      東京
    • Related Report
      2012 Research-status Report
  • [Presentation] 貫通孔付き有水晶体眼内レンズの眼光光学特性および散乱の臨床的検討2012

    • Author(s)
      斎藤彩、安藤和歌子、神谷和孝、五十嵐章史、白谷徹、石井梨絵、清水公也
    • Organizer
      第27回JSCRS学術総会
    • Place of Presentation
      東京
    • Related Report
      2012 Research-status Report
  • [Presentation] 貫通孔付き有水晶体眼内レンズのVaultの経時的変化2012

    • Author(s)
      安藤和歌子、神谷和孝、五十嵐章史、斎藤彩、清水公也
    • Organizer
      第27回JSCRS学術総会
    • Place of Presentation
      東京
    • Related Report
      2012 Research-status Report
  • [Presentation] Phakic IOLの新しい展開2012

    • Author(s)
      神谷和孝
    • Organizer
      Refractive Surgery Update Seminar in Kyoto
    • Place of Presentation
      Kyoto
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] 加齢による眼球光学特性・散乱の定量的検討2012

    • Author(s)
      神谷和孝、小橋英長、石井梨絵、佐藤信之、五十嵐章史、清水公也
    • Organizer
      第66回日本臨床眼科学会
    • Place of Presentation
      京都
    • Related Report
      2012 Research-status Report
  • [Presentation] 有水晶体後房レンズ術後8年の臨床成績2012

    • Author(s)
      五十嵐章史、神谷和孝、清水公也
    • Organizer
      第66回日本臨床眼科学会
    • Place of Presentation
      京都
    • Related Report
      2012 Research-status Report
  • [Presentation] 後房型トーリック有水晶体眼内レンズ(toric ICL)の術後3年の成績2012

    • Author(s)
      小橋英長、神谷和孝、松村一弘、小松真理、五十嵐章史、清水公也
    • Organizer
      第66回日本臨床眼科学会
    • Place of Presentation
      京都
    • Related Report
      2012 Research-status Report
  • [Presentation] 白内障サージャンも必見!トーリック有水晶体眼内レンズをマスターしよう2012

    • Author(s)
      清水公也1、神谷和孝1、市川一夫2、中村友昭3、北澤世志博4(1北里大、2社会保険中京病院、3名古屋アイクリニック、神奈川アイクリニック)
    • Organizer
      第66回日本臨床眼科学会
    • Place of Presentation
      京都
    • Related Report
      2012 Research-status Report
  • [Presentation] 後房型有水晶体眼内レンズ(ICL)挿入術前後の対光反射2012

    • Author(s)
      藤原和子、石川均、神谷和孝、浅川賢、清水公也
    • Organizer
      第116回日本眼科学会総会
    • Place of Presentation
      東京
    • Related Report
      2012 Research-status Report
  • [Presentation] Four-Year Follow-up of Posterior Chamber Phakic IOL With Central Hole Implantation for Myopia

    • Author(s)
      Shimizu K, Kamiya K, Igarashi A
    • Organizer
      ASCRS/ASOA 2013
    • Place of Presentation
      San Francisco
    • Related Report
      2013 Research-status Report
  • [Presentation] 後房型有水晶体眼内レンズ術後の眼球光学特性

    • Author(s)
      神谷和孝、小橋英長、石井梨絵、五十嵐章史、清水公也
    • Organizer
      第116回日本眼科学会総会
    • Place of Presentation
      東京
    • Related Report
      2013 Research-status Report 2012 Research-status Report
  • [Presentation] Visual Performance After Phakic Intraocular Lens Implantation

    • Author(s)
      Kamiya K
    • Organizer
      The 27th Asia Pacific Academy of Ophthalmology Congress
    • Place of Presentation
      釜山
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] 屈折矯正手術

    • Author(s)
      神谷和孝
    • Organizer
      第49回日本眼光学学会総会
    • Place of Presentation
      東京
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] Phakic IOL

    • Author(s)
      神谷和孝
    • Organizer
      第67回日本臨床学科学会
    • Place of Presentation
      神奈川
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] 次世代の屈折矯正手術 ReLEx・Hole ICL

    • Author(s)
      神谷和孝
    • Organizer
      第17回Cornea Update Seminar ・Tokyo
    • Place of Presentation
      東京
    • Related Report
      2013 Research-status Report
    • Invited

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Published: 2013-05-31   Modified: 2019-07-29  

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