Improvements in systemic health indices after cataract surgery

• Project/Area Number: 24592643
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Ophthalmology
• Research Institution: Keio University (2013-2014); International University of Health and Welfare (2012)
• Principal Investigator: AYAKI Masahiko 慶應義塾大学, 医学部, 准教授 (00167967)
• Co-Investigator(Kenkyū-buntansha): NEGISHI Kazuno 慶應義塾大学, 医学部, 准教授 (10228281) ; HATTORI Atsuhiko 東京医科歯科大学, 教養部, 教授 (70183910)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Project Status: Completed (Fiscal Year 2014)
• Budget Amount: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000); Fiscal Year 2014: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000); Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2012: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
• Keywords: 白内障 / 眼内レンズ / 睡眠 / 歩行速度 / 医療福祉 / 生活の質 / 眼科学 / 整形外科学 / ブルーライト / 白内障手術

Outline of Final Research Achievements

Gait speed and sleep quality are health indices related to longevity and mortality. We measured sleep quality, quality of life, and gait speed before and after cataract surgery to evaluate the efficacy of the procedure on systemic health. The study was conducted on more than 200 cataract patients undergoing intra-ocular lens implant surgery. Patients were evaluated using the Pittsburgh Sleep Quality Index (PSQI) and the National Eye Institute Visual Function Questionnaire 25 (VFQ-25; vision-related quality of life) before and then 2 and 7 months after surgery. Four-meter gait speed was also determined. Significant improvements were noted in PSQI, VFQ-25, and gait speed. Our results indicated cataract surgery was effective on systemic health indices in addition to visual restoration. We published our results in three international journals and number of Japanese journals and meetings.

Research Products

• [Journal Article] Increased gait speed after cataract surgery confers longer expected survival. (2014)
  • Author(s): Ayaki M, Negishi K, Tsubota K
  • Journal Title: Asia Pac. J. Ophthalmol Volume: 3 Pages: 267-270
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Rejuvenation effects of cataract surgery with UV blocking intra-ocular lens on circadian rhythm and gait speed. (2014)
  • Author(s): Ayaki M, Negishi K, Tsubota K
  • Journal Title: Rejuvenation Res Volume: 17 Issue: 4 Pages: 359-365
  • DOI: 10.1089/rej.2014.1550
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Improvements in sleep quality and gait speed after cataract surgery. (2013)
  • Author(s): Ayaki,Muramatsu, Negishi, Tsubota
  • Journal Title: Rejuvenation Research Volume: 16 Pages: 35-42
  • Peer Reviewed
• [Presentation] Orthopedic benefits of visual restoration measured with cataract and simulated patients (2014)
  • Author(s): Ayaki M, Nagura T, Toyama Y, Negishi K, Tsubota K.
  • Organizer: Annual meeting of American Academy of Ophthalmology
  • Place of Presentation: Chicago, USA
  • Year and Date: 2014-10-20
• [Presentation] 白内障とＱＯＬ (2014)
  • Author(s): 綾木雅彦
  • Organizer: 第５３回日本白内障学会
  • Place of Presentation: 東京都品川区TKPガーデンシティ品川
  • Year and Date: 2014-09-28
  • Invited
• [Presentation] 水晶体と眼内レンズの着色と睡眠障害 (2014)
  • Author(s): 綾木雅彦
  • Organizer: 第29回JCRS学会
  • Place of Presentation: 福岡県福岡市国際会議場
  • Year and Date: 2014-07-12
  • Invited
• [Presentation] 白内障手術による睡眠障害の改善効果 (2014)
  • Author(s): 綾木雅彦、根岸一乃、久瀬真奈美、森田健、坪田一男
  • Organizer: 第39回日本睡眠学会
  • Place of Presentation: 徳島県徳島市あわぎんホール
  • Year and Date: 2014-07-04
• [Presentation] Rejuvenation effects of cataract surgery with clear intra-ocular lens implantation on gait speed, sleep quality, and metabolic parameters. (2014)
  • Author(s): Ayaki M, Negishi K, Tsubota K
  • Organizer: Annual Meeting of Association of Research in Vision and Ophthalmology
  • Place of Presentation: Orlando, USA
  • Year and Date: 2014-05-05
• [Presentation] 白内障眼内レンズによる歩行速度の増加
  • Author(s): 綾木雅彦、根岸一乃、坪田一男
  • Organizer: 第27回日本眼内レンズ屈折手術学会
  • Place of Presentation: 千葉県浦安市
• [Presentation] 無着色眼内レンズ手術による睡眠障害の改善
  • Author(s): 綾木雅彦、根岸一乃、坪田一男
  • Organizer: 第67回日本臨床眼科学会
  • Place of Presentation: 横浜市
• [Presentation] 無着色眼内レンズ手術による健康指標改善効果
  • Author(s): 綾木雅彦、根岸一乃、坪田一男
  • Organizer: 第37回日本眼科手術学会
  • Place of Presentation: 京都市
• [Presentation] 白内障混濁と睡眠障害
  • Author(s): 綾木雅彦、根岸一乃、坪田一男
  • Organizer: 第20回水晶体研究会
  • Place of Presentation: 大阪市
• [Presentation] 高齢白内障患者の歩行速度と睡眠と視覚機能の質
  • Author(s): 綾木雅彦、村松昌裕、稲福沙織、奥村良彦、根岸一乃、坪田一男
  • Organizer: 第116回日本眼科学会
  • Place of Presentation: 東京
• [Presentation] 白内障眼内レンズ手術による睡眠の改善
  • Author(s): 綾木雅彦、村松昌裕、根岸一乃、坪田一男
  • Organizer: 第27回日本眼内レンズ屈折手術学会
  • Place of Presentation: 東京
• [Presentation] 白内障が歩行速度と睡眠に与える影響
  • Author(s): 綾木雅彦、村松昌裕、根岸一乃、坪田一男
  • Organizer: 第12回日本抗加齢医学学会
  • Place of Presentation: 横浜
• [Presentation] 白内障の混濁型による睡眠への影響
  • Author(s): 綾木雅彦、根岸一乃、坪田一男
  • Organizer: 第39回水晶体研究会
  • Place of Presentation: 東京