| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Outline of Final Research Achievements |
Since 2007, new genotypes of HAdVs had been reported and caused outbreaks in Japan. New genotypes were mainly designed by complete genome sequence (or plural important region). In this study we used syndromic surveillances of to detect outbreaks of HAdVs, rapidly. By using plural PCR applications, rapid typing was possible from 90 ocular samples and 300 respiratory samples.
As the result, respiratory HAdVs were typed as HAdV-1 to -5, HAdV-56, and HAdV-57. Ocular HAdVs were typed as HAdV-1 to -5, HAdV-8, HAdV-11, HAdV-37, HAdV-53, HAdV-54, HAdV-56, HAdV-64, and HAdV-48 related recombinant strain. Novel HAdV-48 related recombinant strain isolated in two area. HAdV-3 was most frequently associated with outbreaks of pharyngoconjunctival fever. HAdV-4 caused respiratory infections among children.
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