| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
It is important to secure visibility during microsurgery. In vitreous surgery, staining and peeling of the internal limiting membrane (ILM) with vital dyes have been widely performed. Recently we have developed Brilliant Blue G (BBG) as a new safety adjuvant for vitreous surgery. BBG was already approved and marketed in Europe Union. In this study, we found that BBG has a neuroprotective advantages. Our data showed that ATP and P2X7 receptor may induce retinal damage in experimental models, which is effectively inhibit by BBG.In this time, we have developed a new surgical viewing system was as a clinical prototype. This system improved intraoperative visibility under air infusion and the BBG staining intensity by sharp cut filter during vitrectomy.
Moreover, we developed a new and economical disposable micro forceps for a microincision vitrectomy surgery that has high performance and versatility from BBG stained ILM during surgery.
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