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Prediction of shock status by Quantified capillary refill time

Research Project

Project/Area Number 24592742
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Emergency medicine
Research InstitutionYokohama City University

Principal Investigator

MORIMURA Naoto  横浜市立大学, 医学(系)研究科(研究院), 教授 (20239685)

Co-Investigator(Kenkyū-buntansha) GOTO Takahisa  横浜市立大学, 医学研究科, 教授 (00256075)
SAKAMOTO Tetsuya  帝京大学, 医学部, 教授 (40365979)
Research Collaborator OHI Yasufumi  
MATSUMORI Kyoko  
OTSUKA Tsuyoshi  
MUGURUMA Takashi  
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Keywords毛細血管再充満時間 / ショック / パルスオキシメータ / 乳酸
Outline of Final Research Achievements

In this study, we tried to quantify the capillary refill time (Q-CRT) measured from a change of light intensity in near infrared and red light before and after the compression of finger nail bed based on a principle of pulse oximeter. Mean value of Q-CRT of healthy adult volunteers was 1.6 seconds. Since there was the difference of measured value of Q-CRT between the examiners, we developed the new device for measurement of Q-CRT by the automatic and constant pneumatic compression to finger nail bed. In addition, we focused on the difference of light intensity during compression of finger nail bed between infra-red and red light (ΔAb). TheΔAb more than 0.06 was well correlated to the status with blood lactate level more than 2.0 mmol/l.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (7 results)

All 2015 2014 2013 2012

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results) Presentation (5 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] A pilot study of quantitative capillary refill time to identify high blood lactate levels in critically ill patients.2015

    • Author(s)
      Morimura N, Takahashi K, Doi T, Ohnuki T, Sakamoto T, Uchida Y, Takahashi H, Fujita T, Ikeda H.
    • Journal Title

      Emergency Medicine Journal

      Volume: 32 Issue: 6 Pages: 444-448

    • DOI

      10.1136/emermed-2013-203180

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] Capillary Transmitted Light Intensity for the Monitoring of Tissue Perfusion:CLIP Study2014

    • Author(s)
      Naoto Morimura , Tetsuya Sakamoto, Kyoko Matsumori, Kohei Takahashi, Tomoki Doi, Tsuyoshi Otsuka, Kyota Nakamura
    • Organizer
      Resuscitation Science Symposium 2014
    • Place of Presentation
      Chicago, USA.
    • Year and Date
      2014-11-07 – 2014-11-09
    • Related Report
      2014 Annual Research Report
  • [Presentation] Quantitative capillary refill time (Q-CRT): A novel technique for the measurement of CRT with its excellent diagnostic accuracy of the status of high blood lactate level in critically ill patients.2013

    • Author(s)
      Morimura N, Takahashi K, Doi T, Ohnuki T, Kobayashi N, Sakamoto T, Uchida Y, Takahashi H, Fujita T, Ikeda H
    • Organizer
      The 18th World Congress on Disaster and Emergency Medicine
    • Place of Presentation
      Manchester, United Kingdom
    • Related Report
      2013 Research-status Report
  • [Presentation] Quantitative capillary refill time (Q-CRT): A novel technique of the CRT measurement by applying the principle of pulse oximeter.2013

    • Author(s)
      Morimura N, Takahashi K, Doi T, Nakamura K, Yumori A, Kawamura Y, Suzuki N, Ishikawa J, Matsumoto J, Harunari N
    • Organizer
      The 26th European Society of Intensive Care Medicine
    • Place of Presentation
      Paris, France
    • Related Report
      2013 Research-status Report
  • [Presentation] 定量化した毛細血管再充満時間(Quantitative capillary refill time:Q-CRT)による高乳酸血症の予測2013

    • Author(s)
      森村 尚登, 高橋 耕平, 土井 智喜, 中村 京太, 石川 淳哉, 松本 順, 野垣 文子, 祐森 章幸, 内倉 淑男, 春成 伸之
    • Organizer
      第40回日本集中治療医学会総会・学術集会
    • Place of Presentation
      長野県松本文化会館(長野県)
    • Related Report
      2012 Research-status Report
  • [Presentation] 定量化した毛細血管再充満時間(Quantitative capillary refill time)による高乳酸血症の予測2012

    • Author(s)
      森村 尚登, 高橋 耕平, 土井 智喜, 中村 京太, 大貫 隆広, 藤田 尚, 池田 弘人, 坂本 哲也
    • Organizer
      第41回日本救急医学会総会・学術集会
    • Place of Presentation
      国立京都国際会館(京都府)
    • Related Report
      2012 Research-status Report
  • [Patent(Industrial Property Rights)] 支援用具、および生体情報取得システム2014

    • Inventor(s)
      森村尚登 小林直樹 他7名
    • Industrial Property Rights Holder
      森村尚登 小林直樹 他7名
    • Industrial Property Rights Type
      特許
    • Filing Date
      2014-03-11
    • Related Report
      2013 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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