A study on the novel pulp diagnosis based on the pulpal blood flow measured by a dental-pulp-selective blood flowmeter.

• Project/Area Number: 24592859
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Conservative dentistry
• Research Institution: Tohoku University
• Principal Investigator: IKAWA Motohide 東北大学, 大学病院, 助教 (80176065)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Project Status: Completed (Fiscal Year 2014)
• Budget Amount: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000); Fiscal Year 2014: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000); Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2012: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
• Keywords: 歯髄 / 血流 / ヒト / レーザードップラー / 診断 / 測定

Outline of Final Research Achievements

The aims of the present study were to estimate the blood flow velocity in human dental pulp and to evaluate the validity of LDF modified for the measurement of slow blood flow. The frequency range of the Doppler shift measured at the teeth with an opaque rubber dam was 4.3 kHz in average. The estimated mean blood flow velocity was 0.18 mm/s in average at the teeth with a dam. Mean blood flow velocities at the upper central incisor of volunteers were estimated using LDF. Blood flow signals at these measurement areas were recorded using two different LDFs: (a) one with a standard blood flow range; and (b) one modified for low blood flow velocity. LDF for low blood flow velocity detected larger and clearer pulsatile blood flow signals from the teeth with dams than did standard LDF. The present results indicate that the velocity of PBF in humans is very low and that LDF modified for the measurement of slow blood flow is appropriate for PBF measure-ment in humans.

Research Products

• [Journal Article] Improvement of the detection of human pulpal blood flow using a laser Doppler flowmeter modified for low flow velocity. (2014)
  • Author(s): Xiaofu Qu, Motohide Ikawa, Hidetoshi Shimauchi
  • Journal Title: Archives of Oral Biology Volume: 59 Issue: 2 Pages: 199-206
  • DOI: 10.1016/j.archoralbio.2013.11.009
  • Peer Reviewed
• [Presentation] メンタルストレスが口唇の血流および酸素飽和度に及ぼす影響 (2014)
  • Author(s): 井川資英
  • Organizer: 第24回 日本産業衛生学会産業医・産業看護全国協議会
  • Place of Presentation: 金沢市文化ホール
  • Year and Date: 2014-09-25 – 2014-09-26
• [Presentation] レーザードップラー血流計を用いたヒト歯髄血流測定の改良に関する研究 その2：低流速用血流計を用いたヒト歯髄血流測定 (2014)
  • Author(s): 井川資英、島内英俊
  • Organizer: 日本歯科保存学会2014年度春季学術大会(第140回)
  • Place of Presentation: びわこホール
  • Year and Date: 2014-06-19 – 2014-06-20
• [Presentation] Measurement of the human pulpal blood flow velocity using a laser Doppler flowmeter (2013)
  • Author(s): Motohide Ikawa
  • Organizer: 2010 IFEA The 9th World Endodontic Congress
  • Place of Presentation: 東京国際フォーラム
• [Presentation] レーザードップラー血流計を用いたヒト歯髄血流測定の改良に関する研究 その１：ヒト歯髄血流速度の測定 (2012)
  • Author(s): 井川資英
  • Organizer: 第137回日本歯科保存学会2012年度秋季学術大会
  • Place of Presentation: 広島市