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Kinetic analysis of cariogenic bacteria on root dentin caries

Research Project

Project/Area Number 24592866
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Conservative dentistry
Research InstitutionOkayama University

Principal Investigator

OHARA NAOKO  岡山大学, 医歯(薬)学総合研究科, 助教 (80301365)

Co-Investigator(Kenkyū-buntansha) YOSHIYAMA Masahiro  岡山大学, 医歯薬学総合研究科, 教授 (10201071)
OHARA Naoya  岡山大学, 医歯薬学総合研究科, 教授 (70223930)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords根面う蝕 / う蝕誘発モデル / う蝕細菌
Outline of Final Research Achievements

In this study, root caries-induced model was constructed in vitro using the oral streptococci or Actinomyces species. With respect to the change of bacterial species and culture conditions, the penetration depth and dentinal tubules diameter into the dentinal tubules in the lesion of root surface caries were analyzed. As the results, it was indicated that the number of colonization and dentin invasion depended on bacterial species. These findings suggest that bacterial infection of root dentin caries are heavily involved in dental caries pathology.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (3 results)

All 2014 2013 2012

All Presentation (3 results)

  • [Presentation] Actinomyces属3菌種による歯根象牙質う蝕の誘発2014

    • Author(s)
      大原直子、大原直也、田中久美子、山路公造、西谷佳浩、吉山昌宏
    • Organizer
      日本歯科保存学会
    • Place of Presentation
      滋賀県大津市
    • Year and Date
      2014-06-19 – 2014-06-20
    • Related Report
      2014 Annual Research Report
  • [Presentation] 細菌バイオミネラリゼーション誘導の試み2013

    • Author(s)
      大原 直子、大原 直也、田中 久美子、澁谷 和彦、横山 章人、山路 公造、西谷 佳浩、 吉山 昌宏
    • Organizer
      日本歯科保存学会 2013年度秋季学術大会
    • Place of Presentation
      秋田市
    • Related Report
      2013 Research-status Report
  • [Presentation] 口腔連鎖球菌による歯根象牙質う蝕の誘発2012

    • Author(s)
      大原直子、田中久美子、澁谷和彦、西谷佳浩、大原直也、吉山昌宏
    • Organizer
      日本歯科保存学会 2012年度秋季学術大会
    • Place of Presentation
      広島市
    • Related Report
      2012 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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