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Application of optical coherence tomography for monitoring of root caries activity

Research Project

Project/Area Number 24592883
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Conservative dentistry
Research InstitutionNihon University

Principal Investigator

KUROKAWA Hiroyasu  日本大学, 歯学部, 助教 (10291709)

Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords光干渉断層画像診断法(OCT) / 根面齲蝕 / 脱灰抑制 / 石灰化 / 光干渉断層画像法(OCT) / S-PRGフィラー / 光干渉断層画像診断法 / 象牙質観察 / OCT
Outline of Final Research Achievements

Effects of a fluoride-releasing varnish on dentin demineralization were examined using optical coherence tomography (OCT). Bovine incisors that were sliced and treated with undersaturated 0.1 M lactic acid buffer solution (DE group). A thin film of varnish was applied before demineralization (Coated group). Control was maintained in artificial saliva. Using OCT of selected locations on the dentin surface, peak intensity (dB) and width (μm) at 1/e2 were obtained and integrated values calculated. Although alterations in integrated values were different in each group, there was a slight but not significant increase in those for the control group and a slight but significant increase for the De group. For the Coated group, integrated values were doubled seven days after experiment initiation, followed by a significant increase. Fluoride-releasing varnish prevented dentin demineralization as detected by optical coherence tomography.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (16 results)

All 2014 2013 2012 Other

All Journal Article (5 results) (of which Peer Reviewed: 5 results,  Open Access: 2 results,  Acknowledgement Compliant: 1 results) Presentation (11 results)

  • [Journal Article] Evaluation of the effects of fluoride-releasing varnish on dentin demineralization using optical coherence tomography2014

    • Author(s)
      Kotaku M, Murayama R, Shimamura Y, Takahashi F, Suzuki T, Kurokawa H, Miyazaki M
    • Journal Title

      Dental Materials Journal

      Volume: 33 Issue: 5 Pages: 648-655

    • DOI

      10.4012/dmj.2014-072

    • NAID

      130004696768

    • ISSN
      0287-4547, 1881-1361
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Optical coherence tomography examination of the effect of S-PRG filler extraction solution on the demineralization of bovine enamel2014

    • Author(s)
      Masayoshi IINO, Ryosuke MURAYAMA, Yutaka SHIMAMURA, Hiroyasu KUROKAWA, Tetsuya FURUICHI,Takayuki SUZUKI, Masashi MIYAZAKI
    • Journal Title

      Dental Materials Journal

      Volume: 33 Issue: 1 Pages: 48-53

    • DOI

      10.4012/dmj.2013-202

    • NAID

      130003394951

    • ISSN
      0287-4547, 1881-1361
    • Related Report
      2013 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] エナメル質表層脱灰の光干渉断層画像解析への1/e2幅の応用2013

    • Author(s)
      三冨純一
    • Journal Title

      日本歯科保存学雑誌

      Volume: 56 Pages: 488-497

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Ultrasonic investigation of the effect of S-PRG filler-containing coating material on bovine tooth demineralization2012

    • Author(s)
      Murayama R
    • Journal Title

      Dental Material Journal

      Volume: Vol31 Pages: 954-959

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] 歯質の乾燥状態が光干渉断層画像に及ぼす影響2012

    • Author(s)
      島村 穣
    • Journal Title

      日本歯科保存学雑誌

      Volume: 55巻 Pages: 333-339

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Presentation] 根面齲蝕をターゲットとした再石灰化療法の確立へのペプチドP11-4の応用2014

    • Author(s)
      高橋史典,黒川弘康,村山良介,瀧本正行,小泉美香,瀧川智義,佐藤幹武,宮崎真至
    • Organizer
      日本歯科保存学会平成26年度秋季大会(第141回)
    • Place of Presentation
      山形テルサ(山形県山形市双葉町)
    • Year and Date
      2014-10-30
    • Related Report
      2014 Annual Research Report
  • [Presentation] OCTをモダリティとしたシーラント填塞状態の観察2014

    • Author(s)
      古宅眞由美,飯野正義,瀧本正行,村山良介,島村 穣,黒川弘康,宮崎真至
    • Organizer
      日本歯科理工学会第64回秋期学術講演会
    • Place of Presentation
      アステールプラザ(広島県広島市中区加古町)
    • Year and Date
      2014-10-04
    • Related Report
      2014 Annual Research Report
  • [Presentation] フッ化物含有CPP-ACPペーストが歯質の脱灰抑制に及ぼす影響2014

    • Author(s)
      鈴木崇之,村山良介,川本 諒,黒川弘康,高見澤俊樹,宮崎真至,日野浦 光,近藤 貢
    • Organizer
      日本歯科保存学会平成26年度春季大会(第140回)
    • Place of Presentation
      びわ湖ホール(滋賀県大津市打出浜)
    • Year and Date
      2014-06-20
    • Related Report
      2014 Annual Research Report
  • [Presentation] 照射レーザの波長が歯質のOCT像に及ぼす影響2013

    • Author(s)
      村山良介,飯野正義,島村 穣,鈴木英梨子,黒川弘康,升谷滋行,宮崎真至,岩崎圭祐
    • Organizer
      日本歯科保存学会2013年度春季学術大会
    • Place of Presentation
      福岡国際会議場(福岡市博多区石城町)
    • Related Report
      2013 Research-status Report
  • [Presentation] 歯質残存厚径測定へのOCTの応用2013

    • Author(s)
      飯野正義,古宅眞由美,生形奈緒子,田村ゆきえ,利根川雅佳,黒川弘康,宮崎真至,細矢由美子,市石芳博,宮 直利
    • Organizer
      日本歯科保存学会2013年度春季学術大会
    • Place of Presentation
      福岡国際会議場(福岡市博多区石城町)
    • Related Report
      2013 Research-status Report
  • [Presentation] 光干渉断層画像法の歯質残存厚径測定への応用

    • Author(s)
      飯野正義
    • Organizer
      第59回日本歯科理工学会学術講演会
    • Place of Presentation
      あわぎんホール(徳島県)
    • Related Report
      2012 Research-status Report
  • [Presentation] 象牙細管の走向がOCTイメージ像に及ぼす影響

    • Author(s)
      島村 穣
    • Organizer
      第136回日本歯科保存学会春季学術大会
    • Place of Presentation
      沖縄コンベンションセンター(沖縄県)
    • Related Report
      2012 Research-status Report
  • [Presentation] 次世代に向けた診査法 光干渉断層画像診断法(OCT)の歯科臨床への応用

    • Author(s)
      黒川弘康
    • Organizer
      第22回日本歯科医学会総会
    • Place of Presentation
      インテックス大阪(大阪府)
    • Related Report
      2012 Research-status Report
  • [Presentation] 象牙質の湿潤状態がOCTイメージに及ぼす影響

    • Author(s)
      島村 穣
    • Organizer
      第137回日本歯科保存学会秋季学術大会
    • Place of Presentation
      広島国際会議場(広島県)
    • Related Report
      2012 Research-status Report
  • [Presentation] OCTによる乳歯の脱灰状況の観察

    • Author(s)
      村山良介
    • Organizer
      第137回日本歯科保存学会秋季学術大会
    • Place of Presentation
      広島国際会議場(広島県)
    • Related Report
      2012 Research-status Report
  • [Presentation] OCTを用いたシーラント填塞状態の観察

    • Author(s)
      古宅眞由美
    • Organizer
      第137回日本歯科保存学会秋季学術大会
    • Place of Presentation
      広島国際会議場(広島県)
    • Related Report
      2012 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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