Project/Area Number |
24592888
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Conservative dentistry
|
Research Institution | Kanagawa Dental College |
Principal Investigator |
SHIIYA Toru 神奈川歯科大学, 大学院歯学研究科, 講師 (40350532)
|
Co-Investigator(Kenkyū-buntansha) |
MUKAI Yoshiharu 神奈川歯科大学, 大学院歯学研究科, 准教授 (40247317)
TERANAKA Toshio 神奈川歯科大学, 歯学部, 名誉教授 (60104460)
|
Project Period (FY) |
2012-04-01 – 2015-03-31
|
Project Status |
Completed (Fiscal Year 2014)
|
Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
|
Keywords | 過再石灰化 / 口腔内モデル / TMR分析 / 象牙質脱灰 / in situ / 根面う蝕 |
Outline of Final Research Achievements |
This study indicated that the novel teeth coating material and the novel resin-based temporary filling material which contained S-PRG filler had remineralization and anti-demineralization effects on dentin in vitro. S-PRG filler could release various types of ions, including fluoride, strontium, sodium, boron, aluminum and silicate ions. However, in situ investigation, daily use of fluoride-containing dentifrice diminished the effect of the materials on root dentin demineralization. Further, among the subjects of lower saliva flow rate, the materials could not bring out the anti-demineralization effects. We would like to establish the system which induces hyper-remineralization on subsurface dentin lesions for even these patients.
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