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Hyper-remineralization strategy for root caries of older persons using the novel intraoral device

Research Project

Project/Area Number 24592888
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Conservative dentistry
Research InstitutionKanagawa Dental College

Principal Investigator

SHIIYA Toru  神奈川歯科大学, 大学院歯学研究科, 講師 (40350532)

Co-Investigator(Kenkyū-buntansha) MUKAI Yoshiharu  神奈川歯科大学, 大学院歯学研究科, 准教授 (40247317)
TERANAKA Toshio  神奈川歯科大学, 歯学部, 名誉教授 (60104460)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords過再石灰化 / 口腔内モデル / TMR分析 / 象牙質脱灰 / in situ / 根面う蝕
Outline of Final Research Achievements

This study indicated that the novel teeth coating material and the novel resin-based temporary filling material which contained S-PRG filler had remineralization and anti-demineralization effects on dentin in vitro. S-PRG filler could release various types of ions, including fluoride, strontium, sodium, boron, aluminum and silicate ions. However, in situ investigation, daily use of fluoride-containing dentifrice diminished the effect of the materials on root dentin demineralization. Further, among the subjects of lower saliva flow rate, the materials could not bring out the anti-demineralization effects. We would like to establish the system which induces hyper-remineralization on subsurface dentin lesions for even these patients.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (15 results)

All 2015 2014 2012 Other

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Acknowledgement Compliant: 1 results) Presentation (13 results)

  • [Journal Article] Effect of the coating material on root dentin remineralization in vitro.2014

    • Author(s)
      Shiiya T, Tomiyama K, Iizuka J, Hasegawa H, Kuramochi E, Fujino F, Ohashi K, Nihei T, Teranaka T, Mukai Y
    • Journal Title

      American Journal of Dentistry

      Volume: 27 Pages: 258-262

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Anti-demineralization effect of a novel fluoride-releasing varnish on dentin2012

    • Author(s)
      Toru Shiiya
    • Journal Title

      American Journal of Dentistry

      Volume: 25 Pages: 347-350

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Presentation] 新規S-PRGフィラー配合バーニッシュの象牙質脱灰抑制能(第2報)2015

    • Author(s)
      片岡あい子,椎谷 亨,藤野富久江,富山 潔,飯塚純子,長谷川晴彦,倉持江里香,大橋 桂,二瓶智太郎,向井義晴
    • Organizer
      日本歯科保存学会2015年度春季学術大会(第142回)
    • Place of Presentation
      北九州
    • Year and Date
      2015-06-25
    • Related Report
      2014 Annual Research Report
  • [Presentation] S-PRGフィラー含有レジン系仮封材の象牙質脱灰抑制能.2015

    • Author(s)
      椎谷 亨,富山 潔,飯塚純子,長谷川晴彦,倉持江里香,藤野富久江,大橋 桂,二瓶智太郎,寺中敏夫,向井義晴
    • Organizer
      神奈川県歯科医師会第13回学術大会
    • Place of Presentation
      横浜
    • Year and Date
      2015-01-25
    • Related Report
      2014 Annual Research Report
  • [Presentation] S-PRGフィラー配合新規バーニッシュの象牙質脱灰抑制能.2014

    • Author(s)
      椎谷 亨,片岡あい子,藤野富久江,富山 潔,飯塚純子,長谷川晴彦,倉持江里香,大橋桂,二瓶智太郎,向井義晴
    • Organizer
      神奈川歯科大学学会第49回総会
    • Place of Presentation
      横須賀
    • Year and Date
      2014-11-29
    • Related Report
      2014 Annual Research Report
  • [Presentation] 新規S-PRGフィラー配合バーニッシュの象牙質脱灰抑制能.2014

    • Author(s)
      片岡あい子,椎谷 亨,藤野富久江,富山 潔,飯塚純子,長谷川晴彦,倉持江里香,大橋桂,二瓶智太郎,向井義晴
    • Organizer
      日本歯科保存学会2014年度秋季学術大会(第141回)
    • Place of Presentation
      山形
    • Year and Date
      2014-10-31
    • Related Report
      2014 Annual Research Report
  • [Presentation] Anti-Demineralization Effect of an S-PRG Temporary Filling Material on Dentin.2014

    • Author(s)
      Shiiya T, Tomiyama K, Iizuka J, Hasegawa H, Kuramochi E, Fujino F, Ohashi K, Nihei T, Teranaka T, Mukai Y
    • Organizer
      The 8th Annual Congress of the Pan European Region of the International Association for Dental Research (PER/IADR)
    • Place of Presentation
      Dubrovnik, Croatia
    • Year and Date
      2014-09-12
    • Related Report
      2014 Annual Research Report
  • [Presentation] PRGバリアコートの根面象牙質再石灰化効果 第3報:塗布直下および隣接部位における獲得耐酸性

    • Author(s)
      椎谷 亨,向井義晴,富山 潔,飯塚純子,長谷川晴彦,倉持江里香,藤野富久江,寺中敏夫
    • Organizer
      日本歯科保存学会2013年度春季学術大会(第138回)
    • Place of Presentation
      福岡国際会議場(福岡県)
    • Related Report
      2013 Research-status Report
  • [Presentation] 新規S-PRGフィラー含有レジン系仮封材の象牙質脱灰抑制能

    • Author(s)
      椎谷 亨,富山 潔,飯塚純子,長谷川晴彦,倉持江里香,藤野富久江,大橋 桂,二瓶智太郎,寺中敏夫,向井義晴
    • Organizer
      日本歯科保存学会2013年度秋季学術大会(第139回)
    • Place of Presentation
      秋田県総合生活文化会館(秋田県)
    • Related Report
      2013 Research-status Report
  • [Presentation] 新規S-PRGフィラー含有レジン系仮封材の象牙質脱灰抑制能

    • Author(s)
      椎谷 亨,富山 潔,飯塚純子,長谷川晴彦,倉持江里香,藤野富久江,大橋 桂,二瓶智太郎,寺中敏夫,向井義晴
    • Organizer
      神奈川歯科大学学会第48回総会
    • Place of Presentation
      神奈川歯科大学(神奈川県)
    • Related Report
      2013 Research-status Report
  • [Presentation] Effect of PRG Barrier Coat on dentin remineralization in vitro

    • Author(s)
      Toru Shiiya
    • Organizer
      6th Annual Congress of the Pan European of the IADR
    • Place of Presentation
      Finlandia Hall (Helsinki, Finland)
    • Related Report
      2012 Research-status Report
  • [Presentation] PRGバリアコートの根面象牙質再石灰化効果

    • Author(s)
      椎谷 亨
    • Organizer
      第136回日本歯科保存学会2012年度春季学術大会
    • Place of Presentation
      沖縄コンベンションセンター(沖縄県)
    • Related Report
      2012 Research-status Report
  • [Presentation] PRGバリアコートの根面象牙質再石灰化効果 第2報:耐酸性試験

    • Author(s)
      椎谷 亨
    • Organizer
      第137回日本歯科保存学会2012年度秋季学術大会
    • Place of Presentation
      広島国際会議場(広島県)
    • Related Report
      2012 Research-status Report
  • [Presentation] PRGバリアコートの根面象牙質再石灰化効果

    • Author(s)
      椎谷 亨
    • Organizer
      神奈川歯科大学学会第47回総会
    • Place of Presentation
      神奈川歯科大学(神奈川県)
    • Related Report
      2012 Research-status Report
  • [Presentation] PRGバリアコートの根面象牙質再石灰化効果 第3報:塗布直下および隣接部位における獲得耐酸性

    • Author(s)
      椎谷 亨
    • Organizer
      第138回日本歯科保存学会2013年度春季学術大会
    • Place of Presentation
      福岡国際会議場(福岡県)
    • Related Report
      2012 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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