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Research and development of the dental material having a functional antibacterial action

Research Project

Project/Area Number 24592917
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Prosthetic dentistry
Research InstitutionHiroshima University

Principal Investigator

NOMURA YUJI  広島大学, 医歯薬保健学研究院, 助教 (80218370)

Co-Investigator(Kenkyū-buntansha) SAWAJIRI Masahiko  広島大学, 医歯薬保健学研究院, 助教 (20325195)
Co-Investigator(Renkei-kenkyūsha) TAKAHASI Toru  熊本保健科学大学, 保健科学部, 教授 (70369122)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords機能的消毒作用 / 二酸化塩素 / 歯科材料 / 歯科器機
Outline of Final Research Achievements

The acid such as lactic acid which bacteria produces in the mouth is one of the cause of the dental caries. So we performed the development of the disinfectant and dental materials which acts effectively when bacteria was producing an acid. The one used for this study is an aqueous solution of chlorine dioxide. Chlorine dioxide possesses a wide antibacterial spectrum and strong sterilizing power on the very low concentration, and the safety to a living body is also high. Using this nature, the functional disinfectant and the dental materials have been developed which indicate the more strong sterilization effect when bacteria possessed an acid production.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (3 results)

All 2014 2012

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results) Presentation (1 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] The extracts of Japanese willow tree species are effective for apoptotic desperation or differentiation of acute myeloid leukemia cells2014

    • Author(s)
      Kounosuke Fujita, Yuji Nomura1, Masahiko Sawajiri1, Pravat K. Mohapatra, Hany A. El-Shemy, Nguyen T. Nguyen, Masashi Hosokawa, Kazuo Miyashita, Teruo Maeda, Hirofumi Saneoka, Shohei Fujita, Takayuki Fujita
    • Journal Title

      Pharmacognosy Magazine

      Volume: 10 Issue: 38 Pages: 125-131

    • DOI

      10.4103/0973-1296.131023

    • Related Report
      2014 Annual Research Report 2013 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] 二 酸化塩素のC.albicans バイオフィルムに対する抗菌効果2012

    • Author(s)
      堀 智治,野 村 雄二,呉本 晃一,貞森 紳丞,赤川 安正
    • Organizer
      第121回日本補綴歯科学会学術大会
    • Place of Presentation
      横浜
    • Related Report
      2012 Research-status Report
  • [Patent(Industrial Property Rights)] 二酸化ハロゲンを含む水溶液製造方法及び水蒸気発生装置2014

    • Inventor(s)
      野村雄二、澤尻昌彦
    • Industrial Property Rights Holder
      野村雄二、澤尻昌彦
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2014-113404
    • Filing Date
      2014-05-13
    • Related Report
      2014 Annual Research Report

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Published: 2013-05-31   Modified: 2019-07-29  

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