Study on bone matrix analysis for prognosis of tooth longevity to establish prosthetic treatment for individuals
| Project/Area Number |
24592945
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Prosthetic dentistry
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| Research Institution | Fukuoka Dental College |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
SATO Hironobu 福岡歯科大学, 歯学部, 教授 (00145955)
TOKUTOMI Kentaro 福岡歯科大学, 歯学部, 助教 (20508981)
KATAFUCHI Michitsuna 福岡歯科大学, 歯学部, 助教 (90454933)
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| Research Collaborator |
YAMAUCHI Mitsuo
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 骨質 / 骨量 / 顎骨 / コラーゲン / 個人差 / 歯の寿命 / 下顎骨 / 翻訳後修飾 / 部位特異性 / 四肢骨 / 歯 / ミネラル / 骨基質 |
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| Outline of Final Research Achievements |
We investigated what extent the individual variation was in mandibular bone quantity and a major bone matrix, collagen, and thier relation to tooth longevity. At the manidibular first molar region, cortical bone showed thicker in men than in women. Men did not exhibit the thickness decrease by age, while women did. Trabecular bone density did not differ by sex and age. A large extent of individual difference exists in the quantities of cortical and trabecular bones. In the mandibular mental region, the bone collagen content showed a large extent among individuals, though the extent of lysine hydroxylation of collagen did a relatively small variarion. The subjects showing larger content of collagen had almost two times as number of the remaining teeth as those showing smaller content of collagen. It is suggested that the mandibles have a large variation of collagen content among individuals and the variation could be a factor for tooth longevity.
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Report
(4 results)
Research Products
(7 results)
