| Project/Area Number |
24593027
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Surgical dentistry
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| Research Institution | Osaka University |
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Principal Investigator |
MASAYA OKURA 大阪大学, 歯学研究科(研究院), 准教授 (10281130)
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| Co-Investigator(Renkei-kenkyūsha) |
OTA Yoshihide 東海大学, 医学部口腔外科, 教授 (60233152)
KURITA Hiroshi 信州大学, 大学院医学研究科, 教授 (10273103)
KIRITA Tadaaki 奈良県立医大, 口腔外科, 教授 (70201465)
UMEDA Masahiro 長崎大学, 大学院医歯薬総合研究科, 教授 (60301280)
YANAMOTO Souichi 長崎大学, 大学院医歯薬総合研究科, 講師 (10315260)
OTSURU Mitsunobu 東海大学, 医学部口腔外科, 講師 (60384864)
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| Research Collaborator |
SUMIOKA Satoshi
YAMAMOTO NAO
LEE Atsushi
SAWAI Natsuko
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 口腔癌 / EBM / 頸部郭清術 / 術後補助療法 / QOL / 遠隔転移 / 術後療法 / 口腔再建 / 口腔がん / 科学的根拠 / 扁平上皮癌 / oral cancer |
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| Outline of Final Research Achievements |
For the purpose of establishing a useful scientific basis in Japan for the treatment of oral cancer, it finished the registration of oral cancer in 1211 patients, and advanced clinical, image, pathology, functional data were integrated and analysed. In addition to Osaka University this study was performed in multicenter study partially with Japanese 6 facilities. As a result, risk factors for distant metastasis of oral cancer was identified, and the significance of adjuvant therapies for oral cancer was clarified. Method of atrophy prevention in sternocleidomastoid sparing neck dissection, N0 neck of treatment strategy decision, proposals of new excellent T classification of the mandibular gingiva cancer, and invasion pattern of tongue cancer were demonstrated. These indicates the unique character of the oral cavity cancer in the head and neck cancer, are thought to be useful in the clinical practice.
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