Evidence Based Medicine for Treatment of Oral Cancer
| Project/Area Number |
24593027
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Surgical dentistry
|
|---|
| Research Institution | Osaka University |
|---|
Principal Investigator |
MASAYA OKURA 大阪大学, 歯学研究科(研究院), 准教授 (10281130)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
OTA Yoshihide 東海大学, 医学部口腔外科, 教授 (60233152)
KURITA Hiroshi 信州大学, 大学院医学研究科, 教授 (10273103)
KIRITA Tadaaki 奈良県立医大, 口腔外科, 教授 (70201465)
UMEDA Masahiro 長崎大学, 大学院医歯薬総合研究科, 教授 (60301280)
YANAMOTO Souichi 長崎大学, 大学院医歯薬総合研究科, 講師 (10315260)
OTSURU Mitsunobu 東海大学, 医学部口腔外科, 講師 (60384864)
|
|---|
| Research Collaborator |
SUMIOKA Satoshi
YAMAMOTO NAO
LEE Atsushi
SAWAI Natsuko
|
|---|
| Project Period (FY) |
2012-04-01 – 2016-03-31
|
| Project Status |
Completed (Fiscal Year 2015)
|
| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
|
|---|
| Keywords | 口腔癌 / EBM / 頸部郭清術 / 術後補助療法 / QOL / 遠隔転移 / 術後療法 / 口腔再建 / 口腔がん / 科学的根拠 / 扁平上皮癌 / oral cancer |
|---|
| Outline of Final Research Achievements |
For the purpose of establishing a useful scientific basis in Japan for the treatment of oral cancer, it finished the registration of oral cancer in 1211 patients, and advanced clinical, image, pathology, functional data were integrated and analysed. In addition to Osaka University this study was performed in multicenter study partially with Japanese 6 facilities. As a result, risk factors for distant metastasis of oral cancer was identified, and the significance of adjuvant therapies for oral cancer was clarified. Method of atrophy prevention in sternocleidomastoid sparing neck dissection, N0 neck of treatment strategy decision, proposals of new excellent T classification of the mandibular gingiva cancer, and invasion pattern of tongue cancer were demonstrated. These indicates the unique character of the oral cavity cancer in the head and neck cancer, are thought to be useful in the clinical practice.
|
Report
(5 results)
Research Products
(62 results)
-
-
[Journal Article] Multicenter Retrospective Study of Adjuvant Therapy for Patients with Pathologically Lymph Node-Positive Oral Squamous Cell Carcinoma: Analysis of Covariance Using Propensity Score.2015
Author(s)
Yanamoto S, Otsuru M, Ota Y, Okura M, Aikawa T, Kurita H, Kamata T, Kirita T, Yamakawa N, Ueda M, Yamashita T, Komori T, Shigeta T, Yokoo S, Ogawa M, Umeda M; Japan Oral Oncology Group.
-
Journal Title
Ann Surg Oncol
Volume: Dec;22 Suppl 3
Issue: S3
Pages: 992-9
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
[Presentation] A Multicenter Retrospective Study of the Clinical Outcomes of Patients with Oral Mucosal Melanoma2015
Author(s)
Takahiro Kamata, Ota Y, Otsuru M, Okura M, Aikawa T, Umeda M, Yanamoto S, Kirita T, Yamakawa N, Yamashita T, Ueda M, Kurita H.
Organizer
39th Annual Meeting of Japan Society for Head and Neck Cance
Place of Presentation
Kobe international conference center, 兵庫県 神戸市
Year and Date
2015-06-03
Related Report
Int'l Joint Research
-
[Presentation] 多施設共同による傾向スコアを用いたT1-2N0M0舌扁平上皮癌に予防郭清を行うことの是非についての後ろ向き研究2015
Author(s)
大鶴 光信, 柳本 惣市, 梅田 正博, 鎌田 孝広, 栗田 浩, 山川 延宏, 桐田 忠昭, 上田 倫弘, 山下 徹郎, 相川 友直, 大倉 正也, 太田 嘉英
Organizer
第６９回日本口腔科学会学術集会
Place of Presentation
大阪国際会議場、大阪府大阪市
Year and Date
2015-05-13
Related Report
-
-
-
-
-
-
[Presentation] 口腔癌術後患者におけるQOL評価2014
Author(s)
山本 奈穂, 相川 友直, 平岡 慎一郎, 木田 久美子, 永谷 俊介, 大倉 正也, 古郷 幹彦
Organizer
第68回 日本口腔科学会
Place of Presentation
京王プラザ（東京都/新宿）
Year and Date
2014-05-07 – 2014-05-09
Related Report
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
