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Elucidation of mechanical condition for controlling destructive alveolar bone resorption under diabetic hyperglycemia

Research Project

Project/Area Number 24593072
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Orthodontic/Pediatric dentistry
Research InstitutionHokkaido University

Principal Investigator

SATO Yoshiaki  北海道大学, 歯学研究科(研究院), 准教授 (00250465)

Co-Investigator(Kenkyū-buntansha) KUSAKABE Toyohisa  北海道大学, 大学病院, 助教 (80322824)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords糖尿病 / 高血糖 / 矯正的歯の移動 / 骨吸収 / 3次元 / 低出力超音波パルス / LIPUS / リモデリング / 3次元解析 / 矯正力による歯の移動 / 歯槽骨 / 破骨細胞 / 持続力 / 矯正力
Outline of Final Research Achievements

Destructive alveolar bone resorption may be occurring by orthodontic tooth movement under diabetic hyperglycemia. The aims of this study were, to know the 3-dimensional alveolar bone resorption rate by orthodontic treatment under hyperglycemia, to know optical orthodontic force in such cases, and to know if the Low-Intensity Pulsed Ultrasound could recover this absorbed alveolar bone effectively.
The results could conclude that destructive alveolar bone resorption was occurred in hyperglycemia condition compared to normal condition in rats, and the Low-Intensity Pulsed Ultrasound could formate faster bone absorption.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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