Development of regenerative medicine of tooth root resorption using phosphorylated pullulan
| Project/Area Number |
24593074
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Orthodontic/Pediatric dentistry
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| Research Institution | Tohoku University |
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Principal Investigator |
IKEDA Etsuko 東北大学, 歯学研究科(研究院), 大学院非常勤講師 (20509012)
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| Co-Investigator(Kenkyū-buntansha) |
YAMAMOTO Teruko 東北大学, 歯学研究科, 教授 (00127250)
TAKESHITA Nobuo 東北大学, 歯学研究科, 助教 (50431515)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 再生医療 / リン酸化プルラン / 歯根 / 歯科 / 歯乳頭細胞 / 石灰化誘導 |
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| Outline of Final Research Achievements |
Tooth root resorption is one of side effects of orthodontic treatment. In the present study, we have performed the basic research directing development of regenerative medicine of the tooth root resorption using a novel biomaterial, phosphorylated pullulan. As a result, we achieved elucidation of the effects of phosphorylated pullulan on cell activities, acquirement of cell seeds, and establishment of cell manipulation technique. These findings will contribute to establishment of the regenerative medicine of the tooth root resorption in the future.
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Report
(4 results)
Research Products
(14 results)
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[Journal Article] Compressive force-produced CCN2 induces osteocyte apoptosis through ERK1/2 pathway2014
Author(s)
K Hoshi, H Kawaki, I Takahashi, N Takeshita, M Seiryu, S A Murshid, T Masuda, T Anada, R Kato, H Kitaura, O Suzuki, T Takano-Yamamoto
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Journal Title
J Bone Miner Res
Volume: 29
Issue: 5
Pages: 1244-1257
DOI
NAID
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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