| Project/Area Number |
24593082
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Orthodontic/Pediatric dentistry
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
SHIMAZAKI Kazuo 東京医科歯科大学, 歯学部附属病院, 助教 (10420259)
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| Co-Investigator(Kenkyū-buntansha) |
ONO Takashi 東京医科歯科大学, 大学院医歯学総合研究科, 教授 (30221857)
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| Co-Investigator(Renkei-kenkyūsha) |
OSHIMA Marie 東京大学, 生産技術研究所, 教授 (40242127)
OMURA Susumu 横浜市立大学, 市民総合医療センター, 准教授 (50145687)
IWAI Toshinori 横浜市立大学, 大学病院, 助教 (00468191)
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| Research Collaborator |
YAJIMA Yasuharu
KITA Soma
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | 外科的矯正治療 / 上顎移動術 / 上下顎移動術 / 呼吸機能 / 上顎骨移動術 |
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| Outline of Final Research Achievements |
The subjects consist of 10 patients with mandibular prognathism who underwent maxillo-mandibular orthognathic surgery with the maxillary upward movement. The three-dimensional (3-D) model of the nasal cavity was reconstructed from the pre- and post-operative CT images (pre-operation: 0.90±0.88 months, post-operation: 11.5±1.27 months). The software used to build the 3-D models and perform the fluid analysis of the nasal respiration was Mimics 17.0 (Materialise) and Fluent 14.0 (Ansys). The inlet velocity was calculated from the flow rate (2.00×10-4 m3/s) and the area of inlet. Using the provided calculation results, we compared the pressure drop of the nasal cavity before and after surgery. By simulating nasal respiration and comparing models, changes in configuration of the nasal cavity with bone trimming in the inferior edge of the pyriform aperture decreased the pressure drop. Furthermore, pressure drop in one third from nostril was greater than other parts of the nasal cavity.
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