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The effects of the orthognathic surgical treatment on upper gastrointestinal function, autonomic nervous and endocrine function.

Research Project

Project/Area Number 24593101
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Orthodontic/Pediatric dentistry
Research InstitutionUniversity of Miyazaki

Principal Investigator

YOSHIDA Maho  宮崎大学, 医学部, 医員 (10535785)

Co-Investigator(Kenkyū-buntansha) YOSHIOKA Izumi  九州歯科大学, 歯学部, 教授 (10305823)
NAGATA Junko  宮崎大学, 医学部, 講師 (50264429)
NOMURA Kaori  宮崎大学, 医学部, 医員 (60626141)
MATSUMOTO Nobuhiro  宮崎大学, 医学部, 助教 (70418838)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords顎変形症 / 下顎前突症 / 顎口腔機能 / 消化管活動 / 睡眠 / 自律神経活動 / 外科的矯正治療 / 消化管運動 / 上部消化管機能
Outline of Final Research Achievements

The purpose of this study is inspection of the hypotheses that upper digestive tract function, autonomic nervous and endocrine function are improved by the improving of the skeletal Class III malocclusion using orthognathic surgical treatment. Cross sectional and Prospective Study were conducted with the 10 Class III malocclusion patients and 10 normal occlusion subjects.
The Maximal voluntary bite force and the occlusal contact area were significantly smaller in the Class III group than in the control group. The Class III patients suggested by significantly higher degree of the Tmax of the 13C-acetate breath test, the LF/HF ratio and the irregularity of gastrointestinal activity rhythm, than for the normal occlusion subjects. After orthognathic surgical treatment, all these values were decreased. These findings suggest that the hypothesis mentioned above is right.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (7 results)

All 2015 2013 2012

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (4 results) (of which Invited: 2 results)

  • [Journal Article] Relationships between occlusal force and morphology using the feature elements of occlusal indices.2013

    • Author(s)
      Igawa,K., Nagata,J., Yamashita,Y.and Sakoda,S.
    • Journal Title

      Journal of Japan Association of Dental Traumatology

      Volume: 9(1) Pages: 23-28

    • NAID

      40019989541

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Risk factors for breakage of biodegradable plate systems after bilateral sagittal split mandibular setback surgery.2013

    • Author(s)
      Yoshioka I, Igawa K, Nagata J, Yoshida M, Baba T, Ichiki T, Kondoh Y, Takamori K, Kashima K, Sakoda S.
    • Journal Title

      Br J Oral Maxillofac Surg

      Volume: 印刷中 Issue: 4 Pages: 307-311

    • DOI

      10.1016/j.bjoms.2012.06.007

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] sagittal split ramus osteotomy for patients with skeletal mandibular prognathism and open bite2013

    • Author(s)
      Yoshioka I, Tanaka T, Habu M, Oda M, Kodama M, Kokuryo S, Kito S, Wakasugi-Sato N, Matsumoto-Takeda S, Seta Y, Fukudome Y, Tominaga K, Sakoda S, Morimoto Y.
    • Journal Title

      Oral Surg Oral Med Oral Pathol Oral Radiol

      Volume: 115 Issue: 4 Pages: 455-65

    • DOI

      10.1016/j.oooo.2012.06.010

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Presentation] 歯科でできる!? 睡眠障害の早期発見と治療2015

    • Author(s)
      永田順子
    • Organizer
      第27回日本小児口腔外科学会
    • Place of Presentation
      シーガイアコンベンションセンター
    • Year and Date
      2015-11-07
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 小児の睡眠障害の診断と治療2015

    • Author(s)
      藤本(野村)かおり
    • Organizer
      第27回日本小児口腔外科学会
    • Place of Presentation
      シーガイアコンベンションセンター
    • Year and Date
      2015-11-07
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 片側下顎頭過形成を伴う顔面非対称症に対して下顎枝矢状分割術後に咬合不正の再発 を認めて下顎頭切除術を行った1症例2015

    • Author(s)
      永田順子、温水佳世子、近藤雄大、井川加織、山下善弘
    • Organizer
      第28回日本顎関節学会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2015-07-04 – 2015-07-05
    • Related Report
      2014 Annual Research Report
  • [Presentation] 睡眠時のブラキシズムが睡眠サイクルと 自律神経機能に及ぼす影響2012

    • Author(s)
      永田順子、吉田真穂、井川加織、 藤本かおり※)、鹿嶋光司、高森晃一、吉岡 泉、迫田隅男
    • Organizer
      第22回日本歯科医学会総会
    • Place of Presentation
      インテックス大阪
    • Related Report
      2012 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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