Novel approach for periodontal regeneration using Nanogel
| Project/Area Number |
24593118
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Periodontal dentistry
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
SHIGERU Oda 東京医科歯科大学, 歯学部附属病院, 准教授 (70160869)
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| Co-Investigator(Kenkyū-buntansha) |
KOBAYASHI Hiroaki 東京医科歯科大学, 大学院医歯学総合研究科, 非常勤講師 (50396967)
KATAGIRI Sayaka 東京医科歯科大学, 大学院医歯学総合研究科, 助教 (60510352)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 歯周病 / 歯周組織再生 / スキャフォルド / ゼラチンハイドロゲル / PDL / rhFGF-2 / ヒト歯根膜細胞 / ナノゲル |
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| Outline of Final Research Achievements |
This study reveled new information about two materials,
1)a tunnel-structured b-tricalcium phosphate(tunnel b-TCP) graft material: The inner surface of the tunnels was partially resorbed and replaced with new bone. New blood vessels were observed inside the lumens of tunnelb-TCP.
2)Biodegradable gelatin sponges incorporating b-tricalcium phosphate (b-TCP) with rhFGF-2: Histometric measurements revealed that new bone height at the experimental sites was significantly greater than that at the control sites.
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Report
(4 results)
Research Products
(16 results)
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[Journal Article] Evaluation of Advanced Dental Technology with Enamel Matrix Derivative and Examination of Prognostic Factors in Periodontal Regenerative Therapy2014
Author(s)
塩山 秀裕, 水谷 幸嗣, 青山 典生, 須田 智也, 田中 敬子, 遠藤 亜希子, 楠 侑香子, 山脇 史寛, 藤 原―高 橋 香, 木下 淳博, 荒川 真一, 小田 茂, 和泉 雄一
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Journal Title
Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology)
Volume: 56
Issue: 3
Pages: 302-313
DOI
NAID
ISSN
0385-0110, 1880-408X
Related Report
Peer Reviewed / Open Access
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[Presentation] Detection of subgingival calculus using optical coherence tomography2012
Author(s)
Masaki Tsubokawa, Akira Aoki, Yoichi Taniguchi,Masanori Sawabe, Kenichiro Ejiri, Tatsuya Akizuki, Shigeru Oda, Koji Mizutani, Yasunori Sumi, Yuichi Izumi
Organizer
98th Annual Meeting American Academy of Periodontology
Place of Presentation
Los Angels, CA, USA
Related Report
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