| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Outline of Final Research Achievements |
In order to apply the bactericidal action of photolysis of hydrogen peroxide to a wide range of civilian goods, I have developed the toothbrush that emits blue visible light from the tip of bristle. A compact size LED was fixed with the head of toothbrush by using a weld technology so that the light could be introduced to the tip of bristle. In addition, the content of hydrogen peroxide contained in commercially available toothpastes and the yield of hydroxyl radical generated by the blue light irradiation of these toothpastes were determined. Based on the determinations, an optimal toothpaste was chosen to be used in a future clinical study. Besides these studies, since it was found that addition of proanthocyanidin, a group of polyphenols, augmented the bactericidal action of photolysis of hydrogen peroxide, it was suggested that a novel toothpaste containing proanthocyanidin could be applicable to the light emitting toothbrush.
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