New concept of periodontal disease as a life-style related disease
| Project/Area Number |
24593174
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Social dentistry
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| Research Institution | Tsurumi University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
HANADA Nobuhiro 鶴見大学, 歯学部, 教授 (70180916)
SHIMODA Shinji 鶴見大学, 歯学部, 教授 (30139620)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 歯周病 / 生活習慣病 / 歯石 / 歯石形成 / 石灰化 |
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| Outline of Final Research Achievements |
We established the artificial dental calculus formation system and investigated the effect of ox-LDL for the formation of dental calculous. By the SEM analysis, clearly distinguished crystals were observed when membrane was immersed in HDL. By the TEM analysis, Hydroxyapatite like crystals was observed when Ca solutions were mixed with LDL or ox-LDL. And Ca/P of the crystals with ox-LDL was highest when compared with LDL, HDL. These results indicated that ox-LDL promote the dental calculus formation.
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Report
(4 results)
Research Products
(10 results)
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[Journal Article] Streptococcus troglodytae sp.nov., from the Chimpanzee Oral Cavity2012
Author(s)
Okamoto M, Imai S, Miyanohara M, Saito W, Momoi Y, Abo T, Nomura Y, Ikawa T, Ogawa T, Miyabe-Nishiwaki T, Kaneko A, Watanabe A, Watanabe S, Hayashi M, Tomonaga M, Hanada N
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Journal Title
Int J Syst Evol Microbiol
Volume: (Epub ahead of print)
Issue: Pt_2
Pages: 418-22
DOI
Related Report
Peer Reviewed
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