| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Outline of Final Research Achievements |
Currently, ozone is being discussed in dentistry as a possible alternative oral antiseptic agent. We have developed the ozone gel which is a glycerin solution containing ozone. The advantages of ozone gel include its long sterilization effect and a lack of an unpleasant smell, as well as the fact that it does not induce resistance in bacteria. In this study, we evaluated the safety of ozone gel in the treatment of oral mucosa irritation as well as its effects on hemostasis and antimicrobial effects. we revealed that ozone gel was very mild to the oral mucosa. The hemostatic ability of ozone gel was almost equal to the Bosmin solution and Liquid Thrombin. The instantaneous antibacterial effect of ozone gel was observed.
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