Development of ozone gel for medicine on preventing and/or treating periodontal disease
| Project/Area Number |
24593179
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Social dentistry
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| Research Institution | Osaka Dental University |
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Principal Investigator |
OH Hourei 大阪歯科大学, 歯学部, 教授 (20213613)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | オゾン ジェル / 歯周疾患 / 歯周病治療薬 / 抗炎症作用 / 止血作用 / 口臭抑制薬 / 細胞増殖能 / オゾン / オゾンジェル / 歯周病 / 歯周組織再生療法 / 再生治療 / 歯周治療薬 / 再生医療 |
|---|
| Outline of Final Research Achievements |
Currently, ozone is being discussed in dentistry as a possible alternative oral antiseptic agent. We have developed the ozone gel which is a glycerin solution containing ozone. The advantages of ozone gel include its long sterilization effect and a lack of an unpleasant smell, as well as the fact that it does not induce resistance in bacteria. In this study, we evaluated the safety of ozone gel in the treatment of oral mucosa irritation as well as its effects on hemostasis and antimicrobial effects. we revealed that ozone gel was very mild to the oral mucosa. The hemostatic ability of ozone gel was almost equal to the Bosmin solution and Liquid Thrombin. The instantaneous antibacterial effect of ozone gel was observed.
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Report
(4 results)
Research Products
(18 results)
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[Presentation] オゾンの局所止血効果2014
Author(s)
益野一哉, 佐藤哲夫, 倉 知子,王 宝禮
Organizer
第57回春季日本歯周病学会学術大会
Place of Presentation
長良川国際会議場（岐阜県,岐阜市））
Year and Date
2014-05-22 – 2014-05-23
Related Report
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[Presentation] オゾン水を用いた歯内療法
Author(s)
廣田健、王 宝禮、塩田剛太郎
Organizer
日本医療・環境オゾン学会第18回研究講演会
Place of Presentation
日本薬学会館長井記念ホール（東京都）
Related Report
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[Book] 獣医療にオゾンを活かす場合2015
Author(s)
鷲巣 誠, 三浦敏明,中室克彦、嵯峨井勝,清水無空,岡本芳晴, 上原愛童, 柴田真治,橋本雄一郎,小畑浩身,柳原唯雄,王 宝禮,伊藤宏泰
Publisher
ファームプレス MVM編集部
Related Report
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