| Project/Area Number |
24593368
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Lifelong developmental nursing
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| Research Institution | University of Miyazaki |
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Principal Investigator |
ETO Nozomu 宮崎大学, 農学部, 准教授 (90232959)
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| Co-Investigator(Kenkyū-buntansha) |
SAKONO Masanobu 宮崎大学, 農学部, 教授 (70253515)
KAWAHARA Satoshi 宮崎大学, 農学部, 教授 (30284821)
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| Co-Investigator(Renkei-kenkyūsha) |
SHINOHARA Hisae 宮崎大学, 教育文化学部, 准教授 (40178885)
SUGANUMA Hiroko 宮崎県立看護大学, 教授 (40405585)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2012: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 乳腺炎 / フルクトース / NFκB / 抗炎症 / 人工ニューラルネットワーク |
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| Outline of Final Research Achievements |
Mastitis is one of the inhibitory factors in breast-feeding. Dietary sucrose increased the severity of mastitis caused by milk stasis. As far as we know, this is the first examination that confirmed experimentally the dietary constituent causes the mastitis. Also, we identified the up-regulated gene cluster in the mammary glands inflamed with sucrose. Furthermore, using a high-throughput food functionality evaluation system, we estimated food constituents having the anti-inflammatory effect. It will be necessary to demonstrate protective efficacy of the mastitis with the food constituent in future.
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