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Elucidation of the action mechanism to nerve cells of the essential oil to use for aromahterapy

Research Project

Project/Area Number 24593423
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Lifelong developmental nursing
Research InstitutionFukuyama Heisei University

Principal Investigator

MISAE SHINOMIYA  福山平成大学, 看護学部, 教授 (80215996)

Co-Investigator(Kenkyū-buntansha) KANOU Yosio  吉備国際大学, 保健科学部・作業療法学科, 教授 (70116200)
JINBO Daiki  昭和大学, 医学部, その他 (60601317)
KITAMURA Mayumi  広島国際大学, 助産学専攻科, 准教授 (90521815)
TUMA Fumiko  福山平成大学, 看護学部・看護学科, 講師 (30572987)
JINTA Ai  福山平成大学, 看護学部・看護学科, 助手 (30615927)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2012: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords精油 / アロマセラピー / 看護援助 / アロマバス / 緩和ケア / 芳香浴 / 蓄積的疲労徴候 / PC12m3細胞 / 神経細胞
Outline of Final Research Achievements

The mechanism of action of essential oils was investigated using PC12m3 cells, i.e., mutant cells susceptible to certain chemicals and stress, and orange essential oil, demonstrating that the orange essential oil activated the PC12m3 cells and promoted neurite outgrowth with favorable effects and without cytotoxicity in humans. The pain was alleviated by essential oil used to reduce menstrual symptoms. Autonomic balance was tested in patients hospitalized in palliative care units, who took an aromatic bath supplemented with essential oil, demonstrating sedative and relaxation effects with reduced physical fatigue. The effects of an aromatic bath on the cumulative fatigue symptoms of nurses working on a psychiatric ward were examined, showing significantly reduced mental symptoms and generally increased autonomic nervous activities.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (6 results)

All 2015 2014 2012

All Journal Article (4 results) (of which Peer Reviewed: 4 results,  Acknowledgement Compliant: 1 results) Presentation (2 results)

  • [Journal Article] 緩和ケア病棟におけるがん患者へのアロマバスの効果の検証2015

    • Author(s)
      四宮美佐恵
    • Journal Title

      インターナショナルNursing Care Reserch

      Volume: 第14巻第1号 Pages: 3140-3140

    • NAID

      40020464702

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Neurite Outgrowth of PC12 Mutant Cells Induced by Orange Oil and2012

    • Author(s)
      Misae Shinomiya, Kenji Kawamura, Emiko Tanida, Megumi Nagoshi Hirotoshi Motoda, Yoshiko Kasanami, Fukumi Hiragami, and Yoshio Kano
    • Journal Title

      Acta Medica Okayama

      Volume: 66(2) Pages: 111-118

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] アロマテラピーに用いる精油の神経細胞への作用機序の解明2012

    • Author(s)
      四宮美佐恵
    • Journal Title

      看護・保健科学研究誌

      Volume: 12(1) Pages: 87-94

    • NAID

      40019307788

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] 月経随伴症状に対するアロマテラピーの効果の検証2012

    • Author(s)
      四宮美佐恵,上野愛香,岡田優子,高田のり子
    • Journal Title

      インターナショナルNursing Care Reserch

      Volume: 11(1) Pages: 61-71

    • NAID

      40019304647

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Presentation] 緩和ケア病棟におけるがん患者へのアロマバスの効果に関する研究2014

    • Author(s)
      甚田愛
    • Organizer
      第45回日本看護学会ー慢性期看護
    • Place of Presentation
      アスティ徳島
    • Year and Date
      2014-09-11 – 2014-09-12
    • Related Report
      2014 Annual Research Report
  • [Presentation] Elucidation of the Action Mechanism of Oil Used Aromatherapy on Neurons2012

    • Author(s)
      Misae Shinomiya,Fumiko Tuma,Takayo Kimiya,Megumi Nagoshi,Daiki Jinbo,Yosio Kanou
    • Organizer
      The 1st International Congress of Aromatherapy
    • Place of Presentation
      国立京都国際会館
    • Related Report
      2012 Research-status Report

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Published: 2013-05-31   Modified: 2021-12-20  

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