| Project/Area Number |
24601008
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
医学物理学・放射線技術学
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| Research Institution | Kanazawa University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KAWAI Keiichi 金沢大学, 保健学系, 教授 (30204663)
HANAOKA Hirofumi 千葉大学, 薬学研究科, 助教 (50361390)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | SPECT / 半導体検出器 / 分子イメージング / 小動物用イメージング装置 / 定量測定 / 核医学 / PET / 小動物イメージング / 脳機能 / 腎機能 / 画像解析 |
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| Outline of Final Research Achievements |
In this study, we developed a quantitative measurement on a new small animal SPECT/CT scanners with a semiconductor detecotor.After assessment of performance on the scanners,seinsitivity of pinhole collimators was lower than that of parallel and slit collimators, while resolution was higher. Especially, eXplore speCZT CT120 was superior to another scanner on energy resolution. In addition, attenuation and resolution correction have kept quaitification of radioactive counts.However, we needed to develop new pinhole collimators for mice to yield higher resolution and for rats to yield higher sensitivity. The collimators provided 1.7 times resoulution for mice imaging and 2-3 times sensitivity for rats imaging.
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