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Feasibility Study of an Axially Extendable Multiplex Cylinder PET

Research Project

Project/Area Number 24601019
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field 医学物理学・放射線技術学
Research InstitutionNational Institute of Radiological Sciences

Principal Investigator

YOSHIDA Eiji  独立行政法人放射線医学総合研究所, 分子イメージング研究センター, 主任研究員 (50392246)

Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2012: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
KeywordsPET / 3次元検出器 / 検出器 / シミュレーション
Outline of Final Research Achievements

Current clinical PET scanners have a 20 cm axial field-of-view (FOV). These scanners image the whole body using six or more bed positions. We designed an axially extendable multiplex cylinder (AEMC) PET scanner to provide high versatility for clinical and research studies using semiconductor photo-sensor based, depth-of-interaction (DOI) detectors. The AEMC-PET scanner consists of multiple independent and laminated detector rings using the DOI detectors. The AEMC-PET scanner can extend the axial FOV as each stacked detector ring can be slid sideways. We expect the designed AEMC-PET scanner will provide high versatility in applications such as for measuring whole-body tracer uptakes while keeping the continuous axial FOV; as well, the scan time for static images will be reduced for a comparable number of detectors as conventional PET scanners.
Also, we developed prototype detector using the digital photon counters. The developed detector had high energy resolution of 192 ps.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (13 results)

All 2015 2014 2013 2012

All Journal Article (4 results) (of which Peer Reviewed: 4 results,  Acknowledgement Compliant: 2 results) Presentation (9 results)

  • [Journal Article] Parameter optimization of a digital photon counter coupled to a four-layered DOI crystal block with light sharing2015

    • Author(s)
      E. Yoshida, I. Somlai-Schweiger, H. Tashima, S. I. Ziegler, T. Yamaya
    • Journal Title

      IEEE Transactions Nuclear Sciences

      Volume: 63 Pages: 1-8

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Sensitivity booster for DOI-PET scanner by utilizing Compton scattering events between detector blocks2014

    • Author(s)
      E. Yoshida, H. Tashima, T. Yamaya
    • Journal Title

      Nuclear Instruments and Methods in Physics Research Section A

      Volume: 763 Pages: 502-509

    • DOI

      10.1016/j.nima.2014.07.002

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Feasibility study of an axially extendable multiplex cylinder PET2013

    • Author(s)
      E.Yoshida, Y.Hirano, H.Tashima, N.Inadama, F.Nishikido, H.Murayama, H.Ito, T.Yamaya
    • Journal Title

      IEEE Transaxial Nuclear Sciences

      Volume: 60 Issue: 5 Pages: 3227-3234

    • DOI

      10.1109/tns.2013.2280633

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Spatial resolution limits for the isotropic-3D PET detector X’tal cube2013

    • Author(s)
      E.Yoshida, H.Tashima, Y.Hirano, N.Inadama, F.Nishikido, H.Murayama, T.Yamaya
    • Journal Title

      Nuclear Instrument and Method section A

      Volume: 728 Pages: 107-110

    • DOI

      10.1016/j.nima.2013.06.104

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] Optimization of Digital SiPMs Coupled to a Four-Layered DOI Crystal Block with Light Sharing2014

    • Author(s)
      Eiji Yoshida
    • Organizer
      IEEE Nuclear Science Symposium and Medical Imaging Conference
    • Place of Presentation
      Seattle, USA
    • Year and Date
      2014-11-10 – 2014-11-15
    • Related Report
      2014 Annual Research Report
  • [Presentation] 検出器間散乱を用いた DOI-PET 装置の高感度化手法の開発2014

    • Author(s)
      吉田英治
    • Organizer
      応用物理学関係連合講演会
    • Place of Presentation
      札幌
    • Year and Date
      2014-09-16 – 2014-09-19
    • Related Report
      2014 Annual Research Report
  • [Presentation] 検出期間散乱を用いたDOI-PET装置の高感度化手法の開発2014

    • Author(s)
      吉田英治
    • Organizer
      日本医学物理学会学術大会
    • Place of Presentation
      神奈川
    • Year and Date
      2014-04-10 – 2014-04-13
    • Related Report
      2014 Annual Research Report
  • [Presentation] コンプトン散乱を用いたPET装置の高感度化手法の開発2013

    • Author(s)
      吉田英治,田島英朗,伊藤 浩, 山谷泰賀
    • Organizer
      第53回日本核医学会学術総会
    • Place of Presentation
      福岡
    • Related Report
      2013 Research-status Report
  • [Presentation] アキシャルシフト型シングルリングOpenPETの性能評価2013

    • Author(s)
      吉田英治,品地哲弥,田島英朗, 羽石秀昭, 伊藤 浩, 山谷泰賀
    • Organizer
      第53回日本核医学会学術総会
    • Place of Presentation
      福岡
    • Related Report
      2013 Research-status Report
  • [Presentation] 体軸視野サイズ可変型の新しいPET装置の提案2013

    • Author(s)
      吉田英治,平野祥之,田島英朗,稲玉直子,錦戸文彦,村山秀雄,伊藤 浩, 山谷泰賀
    • Organizer
      第105回日本医学物理学会学術大会
    • Place of Presentation
      神奈川
    • Related Report
      2013 Research-status Report
  • [Presentation] Sensitivity Booster for DOI-PET by Utilizing Compton Scattering Events Between Detector Blocks2013

    • Author(s)
      E.Yoshida, H.Tashima, T.Yamaya
    • Organizer
      2013 IEEE Nuclcear Science Symposium & Medical Imaging Conference
    • Place of Presentation
      Souel
    • Related Report
      2013 Research-status Report
  • [Presentation] 体軸視野サイズ可変型の新しいPET装置の提案2013

    • Author(s)
      265. 吉田英治,平野祥之,田島英朗,稲玉直子,錦戸文彦,村山秀雄,伊藤 浩, 山谷泰賀
    • Organizer
      第105回日本医学物理学会学術大会
    • Place of Presentation
      神奈川、日本
    • Related Report
      2012 Research-status Report
  • [Presentation] Feasibility Study of an Axially Extendable Multiplex Cylinder PET2012

    • Author(s)
      127. E. Yoshida, Y. Hirano, H. Tashima, N. Inadama, F. Nishikido, H. Murayama, H. Ito, T. Yamaya
    • Organizer
      2012 IEEE Nuc. Sci. Sympo. & Med. Imag. Conf
    • Place of Presentation
      Anaheim, USA
    • Related Report
      2012 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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