| Project/Area Number |
24614001
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Integrated Nutrition Science
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| Research Institution | Kitasato University |
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Principal Investigator |
MAKAYA Miyuki 北里大学, 看護学部, 准教授 (60415552)
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| Co-Investigator(Kenkyū-buntansha) |
TSUTSUI Hiroyuki 北海道大学, 医学研究科, 教授 (70264017)
KINUGAWA Shintaro 北海道大学, 医学研究科, 講師 (60399871)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 慢性心不全 / 栄養 / 臨床疫学 / Quality of life / 生命予後 / 疫学 / 栄養疫学 |
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| Outline of Final Research Achievements |
The present study demonstrated that malnutrition in approximately half of patients with chronic heart failure (HF), and malnourished patients had low fatty acid and amino acid levels. Malnourished patients also exhibited reduced exercise tolerance and quality of life (QOL), as well as concurrent depressive symptoms. Patients with depressive symptoms and patients with reduced QOL were found to have significantly lower intake of vegetables, pulses, seaweed, and fruit. We found that malnutrition and dietary habits was closely associated with poor clinical outcomes in patients with HF. Therefore, patient outcome-based nutritional intervention for HF patients is needed.
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