Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
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Outline of Final Research Achievements |
One of the most interesting topics in omics is the development of in situ analysis techniques for biomolecules. In this study, a biomonitoring system that makes it possible to ionize low molecular weight biomolecules selectively and in situ has been developed using accurate corona discharges and mass spectrometry. The accurate corona discharges lead to the regular formation of atmospheric negative ions with various different gas-phase acidities, which serve as reactant ions to ionize gas-phase analytes via ion-molecule reactions. The system developed here can provide the information about both molecular weight and structure of a given analyte, which contributes towards the application to unknown compound analysis.
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