Physiological study of the pathogenesis of akathisia with respect to periodic limb movement
| Project/Area Number |
24621006
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
睡眠科学
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| Research Institution | Shimane University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
OKAZAKI Shihou 島根大学, 医学部, 助教 (20379671)
YASUDA Hideaki 島根大学, 医学部, 助教 (30379680)
MIYAOKA Tsuyoshi 島根大学, 医学部, 准教授 (50284047)
WAKE Rei 島根大学, 医学部, 講師 (60609262)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 周期性四肢運動 / 脊髄自動反射 / バビンスキー反射 / ワンテンベルグ反射 / アカシジア / ワルテンベルグ反射 |
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| Outline of Final Research Achievements |
We investigated the recording of the periodic limb movements with the patients with akathisia using polysomnography and videotape recordings. As a result, we had 3 important new findings by our this research.
① No restriction of the daytime subject’s movement could be obtained using the PolymateⅡ.② Nocturnal sleep stages such as slight and deep non-REM sleep and REM sleep could be judged.③ And, the analizing time shortening and the precise accuracy could be taken using the videotape recording with myogram.
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Report
(4 results)
Research Products
(37 results)
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[Journal Article] Minocycline improves recognition memory and attenuates microglial activation in Gunn rat.a possible hyperbilirubinemia-induced animal model of schizophrenia.2014
Author(s)
Liaury K, Miyaoka T, Tsumori T, Furuya M, Hashioka S, Wake R, Tsuchie K, Fukushima M, Limoa E, Tanra AJ, Horiguchi J
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Journal Title
Prog Neuropsychopharmacol Biol Psychiatry.
Volume: 50
Pages: 184-190
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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[Journal Article] The effects of combine treatment of memantine and donepezil on Alzheimer's disease patients and its relationship with cerebral blood flow in the prefrontal area.2014
Author(s)
Araki T, Wake R, Miyaoka T, Kawakami K, Nagahama M, Furuya M, Limoa E, Liaury K, Hashioka S, Murotani K, Horiguchi J
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Journal Title
Int J Geriatr Psychiatry
Volume: 29(9)
Pages: 881-889
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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[Journal Article] Yokukansan(TJ-54) for treatment of very-late-onset schizophrenia-like psychosis: An open-label study.2013
Author(s)
Miyaoka T, Wake R, Furuya M, Liaury K, Ieda M, Kawakami K, Tsuchie K, Fukushima M, Ishihara K, Araki T, Hashioka S and Horiguchi J
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Journal Title
Phytomedicine
Volume: 20(7)
Pages: 654-658
Related Report
Peer Reviewed
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[Journal Article] Yokukansan(TJ-54) for treatment of very-late-onset Schizophrenia-like psychosis. An open- Label Study Authors.2012
Author(s)
Miyaoka T, Wake R, Furuya M, Liaury K, Ieda M, Kawakami K, Tsuchie K, Fukushima M, Ishihara K, Araki T, Hashioka S, Horiguchi J
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Journal Title
Phytomedicine
Volume: 20(7)
Pages: 654-8
Related Report
Peer Reviewed
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[Journal Article] Minocycline as adjunctive therapy for patients with unipolar psychotic depression: an open-label study.2012
Author(s)
Miyaoka T, Wake R, Furuya M, Liaury K, Ieda M, Kawakami K, Tsuchie K, Taki M, Ishihara K, Araki T, Horiguchi J
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Journal Title
Prog Neuropsychopharmacol Biol Psychiatry
Volume: 37(2)
Pages: 222-6
Related Report
Peer Reviewed
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[Presentation] Efficacy and Safety of Yokukansan(TJ-54) for Treatment-Resistant Schizophrenia:A Randmized,Multi-centre,Double blind,Placebo-controlled Trial.2013
Author(s)
Miyaoka T, Furuya M, Horiguchi J, Wake R, Hashioka S, Toyama M, Daimon T, Mori N, Minabe Y, Iyo M, Ueno S, Ezoe S, Hosyino S, Seno H
Organizer
Society of Biological Psychiatry 68th Annual Meeting.
Place of Presentation
(California San Francisco) Ｈｉｌｔｏｎ Ｕｎｉｏｎ Ｓｑｕａｒｅ
Related Report
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[Presentation] Yokukansan(TJ-54) for treatment of very-late-onset schizophrenia-like psychosis: an open-label study.2013
Author(s)
Miyaoka T, Wake R, Furuya M, Liaury K, Ieda M, Kawakami K, Tsuchie K, Fukushima M, Ishihara K, Araki T, Hashioka S, Horiguchi J
Organizer
The3rd Asian Congress of Schizophrenia Research.
Place of Presentation
Indonesia(Bali)
Related Report
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[Presentation] The effects of minocycline on the CD 11b expression of the microglial cells in the dentate gyrus of Gunn rat: a possible animal model of schizophrenia.2012
Author(s)
Liaury K, Miyaoka T, Tsumori T, Furuya M, Wake R, Ieda M, Tsuchie K, Fukushima M, Ishihara K, Tanra A, Horiguchi J
Organizer
The 35th Annual Meeting of the Japan Neuroscience Society.
Place of Presentation
Nagoya Congress Center
Related Report
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[Presentation] Yokukansan(TJ-54) for treatment of very-late-onset schizophrenia-like psychosis: an open-label study.2012
Author(s)
Miyaoka T, Wake R, Furuya M, Liaury K, Ieda M, Kawakami K, Tsuchie K, Fukushima M, Ishihara K, Araki T, Hashioka S, Horiguchi J
Organizer
12th Annual Meeting of the International College of Geriatric Psychoneuropharmacology
Place of Presentation
Spain(Sevilia)
Related Report
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[Book] 抑肝散2014
Author(s)
堀口淳
Total Pages
12
Publisher
臨牀と研究
Related Report
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