Establishing a new method to analyze neuronal activities of all individual neurons of C. elegans CNS.
| Project/Area Number |
24650167
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Neuroscience in general
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| Research Institution | Kyushu University |
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Principal Investigator |
ISHIHARA Takeshi 九州大学, 理学(系)研究科(研究院), 教授 (10249948)
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| Co-Investigator(Renkei-kenkyūsha) |
TERAMOTO Takayuki 九州大学, 大学院理学研究院, 准教授 (90571836)
KUGE Sayuri 九州大学, 大学院理学研究院, 学術研究員 (50260104)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 神経科学 / イメージング / 線虫 / 情報処理 |
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| Outline of Final Research Achievements |
To visualize the informational processing in CNS, we planned to device a method that enable us to analyze the activities of all individual neurons in living C. elegans. To do this, we improved a microscopy system, optimized Ca2+ probe and image processing including tracking neurons by pattern matching. By using this system, we succeeded in evaluating more than 20 individual neurons and in observing a synchronous activity.
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Report
(4 results)
Research Products
(17 results)
