Development of a novel technique for the trans-synaptic gene manipulation
| Project/Area Number |
24650175
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Neuroscience in general
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| Research Institution | Institute of Physical and Chemical Research |
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Principal Investigator |
FUJIMOTO Satoshi 独立行政法人理化学研究所, 発生・再生科学総合研究センター, 研究員 (50586592)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2013: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 神経回路形成 / マウス / 遺伝子改変 |
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| Research Abstract |
Neural circuits are established by specific neuronal connections via synapses. Therefore, gene manipulation system in a circuit level could be a powerful tool to understand the structural basis of neural computation. In this study, we attempted to make a novel genetically-encoded protein that enables us to trans-synaptically visualize and manipulate a specific neural circuit.
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Report
(3 results)
Research Products
(16 results)
