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Exploration of human brain-specific structures through direct examination of human brain itself

Research Project

Project/Area Number 24650179
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Nerve anatomy/Neuropathology
Research InstitutionKumamoto University

Principal Investigator

FUKUDA Takaichi  熊本大学, 大学院生命科学研究部, 教授 (50253414)

Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywordsヒト脳 / 海馬 / 腹側線条体 / 脳室下帯 / 記憶 / ヒト / モジュール / ヒトの海馬
Outline of Final Research Achievements

Every researcher in neuroscience will agree that the final goal of the study is to understand the human brain. However, due to various restrictions regarding the use of human brains, experimental animals are instead used for sophisticated researches. On the other hand, not so much attention has been payed to detailed structure of the human brain. The present study aimed to find the human brain-specific structures that can be elucidated only by directly analyzing the human brain itself. Complete serial sections were prepared from brain hemispheres, processed for histological studies, and analyzed using computer-assisted three-dimensional tracing system. We found novel modular structures in the human hippocampus that did not exist even in monkey brains. The modules showed periodical patterns inside the hippocampus that have not been described so far. Moreover, we also revealed human-specific structures in the ventral striatum (olfactory tubercle) and in the rostral migratory stream.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (1 results)

All 2015

All Presentation (1 results)

  • [Presentation] マウス海馬台の構造に関する免疫組織化学的研究2015

    • Author(s)
      石原義久、福田孝一
    • Organizer
      第120回日本解剖学会全国学術集会
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2015-03-21 – 2015-03-23
    • Related Report
      2014 Annual Research Report

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Published: 2013-05-31   Modified: 2019-07-29  

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