Regulation of brain region-dependent differentiation of neurons

• Project/Area Number: 24650202
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Neurochemistry/Neuropharmacology
• Research Institution: Keio University
• Principal Investigator: NAKAJIMA Kazunori 慶應義塾大学, 医学部, 教授 (90280734)
• Project Period (FY): 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000); Fiscal Year 2012: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
• Keywords: 脳・神経 / 神経科学 / 発生・分化 / 細胞分化

Research Abstract

We have performed co-culture experiments of embryonic mouse-derived medial ganglionic eminence (MGE) cells (cortical interneuron progenitors) and neonatal anterior or posterior cortical cells. When the MGE cells were co-cultured with anterior cortical cel

Research Products

• [Presentation] Evolution and functional significance of inhibitory interneurons in the cerebral cortex", ワークショップ:"Functions and dysfunctions of inhibitory neurons(抑制性ニューロンの機能と病態) (2012)
  • Author(s): Kazunori Nakajima
  • Organizer: 第35回日本分子生物学会年会
  • Place of Presentation: 福岡国際会議場・マリンメッセ福岡、福岡
  • Year and Date: 2012-12-14
• [Presentation] 動く細胞がみせる大脳皮質層形成のメカニズム (2012)
  • Author(s): 仲嶋一範
  • Organizer: 奈良先端科学技術大学院大学バイオサイエンス研究科セミナー
  • Place of Presentation: 奈良(奈良県)
  • Year and Date: 2012-12-07
• [Presentation] 大脳皮質の形作りのしくみ (2012)
  • Author(s): 仲嶋一範
  • Organizer: 奈良先端科学技術大学院大学動物科学特論講義
  • Place of Presentation: 奈良(奈良県)
  • Year and Date: 2012-12-07
• [Presentation] Keynote Lecture: Neuronal migration and layer formation in the developing cerebral neocortex", Symposium (2012)
  • Author(s): Kazunori Nakajima
  • Organizer: Annual Meeting of Korean Associations of Anatomists
  • Place of Presentation: Buyeo, Korea
  • Year and Date: 2012-10-20
• [Presentation] 大脳皮質神経細胞社会の形成機構 (2012)
  • Author(s): 仲嶋一範
  • Organizer: 東京大学大学院医学系研究科 医学共通講義VII「神経科学入門」
  • Place of Presentation: 東京大学本郷キャンパス、東京
  • Year and Date: 2012-09-11
• [Presentation] Neuronal migration and layer formation in the developing cerebral cortex (2012)
  • Author(s): Kazunori Nakajima
  • Organizer: The 4th Biennial Symposium on Brain and Mind Research in the Asia-Pacific
  • Place of Presentation: Mita Campus, Keio University, Tokyo
  • Year and Date: 2012-08-31
• [Presentation] Development of the cerebral cortex (2012)
  • Author(s): Kazunori Nakajima
  • Organizer: Keio-Karolinska-Peking Joint Summer School 2012
  • Place of Presentation: Keio University, Tokyo
  • Year and Date: 2012-08-03
• [Presentation] Neuronal migration and layer formation in the developing cerebral cortex (2012)
  • Author(s): Kazunori Nakajima
  • Organizer: The 4th Biennial Symposium on Brain and Mind Research in the Asia-Pacific (APRU-BMAP 2012/FIRST 2012 Symposium) “Diseases and Evolution of the Brain and Mind”
  • Place of Presentation: Mita Campus, Keio University, Tokyo
  • Invited
• [Presentation] Keynote Lecture: Neuronal migration and layer formation in the developing cerebral neocortex. Symposium “Cell migration and histogenesis”(organizer: Woong Sun) (2012)
  • Author(s): Kazunori Nakajima
  • Organizer: Annual Meeting of Korean Associations of Anatomists
  • Place of Presentation: Buyeo, Korea
  • Invited
• [Presentation] Evolution and functional significance of inhibitory interneurons in the cerebral cortex. ワークショップ：“Functions and dysfunctions of inhibitory neurons（抑制性ニューロンの機能と病態）” (2012)
  • Author(s): Kazunori Nakajima
  • Organizer: 第35回日本分子生物学会年会
  • Place of Presentation: 福岡国際会議場・マリンメッセ福岡、福岡（福岡県）
  • Invited
• [Presentation] Development of the cerebral cortex
  • Author(s): Kazunori Nakajima
  • Organizer: Keio-Karolinska-Peking Joint Summer School 2012
  • Place of Presentation: Shinanomachi Campus, Keio University, Tokyo
  • Invited
• [Presentation] 大脳皮質神経細胞社会の形成機構
  • Author(s): 仲嶋一範
  • Organizer: 東京大学大学院医学系研究科 医学共通講義VII「神経科学入門」
  • Place of Presentation: 東京大学本郷キャンパス、東京
  • Invited
• [Presentation] 大脳皮質の形作りのしくみ
  • Author(s): 仲嶋一範
  • Organizer: 奈良先端科学技術大学院大学動物科学特論講義
  • Place of Presentation: 奈良先端科学技術大学院（奈良県）
  • Invited
• [Presentation] 動く細胞がみせる大脳皮質層形成のメカニズム
  • Author(s): 仲嶋一範
  • Organizer: 奈良先端科学技術大学院大学バイオサイエンス研究科セミナー
  • Place of Presentation: 奈良先端科学技術大学院（奈良県）
  • Invited
• [Book] 脳神経科学イラストレイテッド (2013)
  • Author(s): 山川眞以、田畑秀典、仲嶋一範
  • Publisher: 羊土社
• [Book] 「神経細胞の移動と皮質の構築」、改訂第３版 脳神経科学イラストレイテッド「神経細胞の移動と皮質の構築」 (2013)
  • Author(s): 山川眞以、田畑秀典、仲嶋一範
  • Total Pages: 397
  • Publisher: 羊土社
• [Book] 実験医学別冊 目的別で選べる遺伝子導入プロトコール (2012)
  • Author(s): 楠澤さやか、仲嶋一範
  • Publisher: 羊土社
• [Book] 「分散した神経細胞へのキュベット電極を用いた遺伝子導入 （in エレクトロポレーション法による神経細胞への導入）」、実験医学別冊 目的別で選べる遺伝子導入プロトコール（仲嶋一範、北村義浩、武内恒成 編集） (2012)
  • Author(s): 楠澤さやか、仲嶋一範
  • Total Pages: 250
  • Publisher: 羊土社