• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Creation of nanodiamond for bioimaging by low-dose ion implantation

Research Project

Project/Area Number 24650278
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Biomedical engineering/Biological material science
Research InstitutionShiga University of Medical Science

Principal Investigator

INUBUSHI Toshiro  滋賀医科大学, 分子神経科学研究センター, 名誉教授 (20213142)

Research Collaborator NAGAMACHI Shinji  滋賀医科大学, 分子神経科学研究センター, 客員教授 (80447002)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywordsナノダイヤモンド / イオン注入 / 蛍光 / 空孔 / イメージング / ナノ素材 / NVセンター / SiVセンター / 金属イオン / ヘリウム / ダイヤモンド
Outline of Final Research Achievements

Nanodiamond(ND) has received increasing attention for its promising biomedical applications. The fluorescence of ND can be substantially enhanced when vacancy is introduce by high-energy particle beam and then annealing to form negatively charged nitrogen-vacancy centers. In this project bright color center in diamond was explored by low-dose ion implantation.
To create fluorescent SiV center, He and Si were co-implanted to commercially available ND. However, trace of SiV center was not detected in regular implantation and annealing conditions. This is probably because the formation of NV due to the originally contaminated nitrogen may humper the creation of SiV center. Considering from these results, single- and polycrystalline diamonds were chosen. As a result, the key techniques concerning the color center associated with vacancy in diamond have been developed and the possible avenues have been introduced for their application to biomedicine.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (1 results)

All 2014

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results)

  • [Journal Article] A Polymer-Based Magnetic Resonance Tracer for Visualization of Solid Tumors by 13C Spectroscopic Imaging2014

    • Author(s)
      Suzuki Y, Iida M, Miura I, Inubushi T, Morikawa S.
    • Journal Title

      Plos One

      Volume: 9(7) Issue: 7 Pages: e102132-e102132

    • DOI

      10.1371/journal.pone.0102132

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access

URL: 

Published: 2013-05-31   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi