Selective elimination of a specific component from alloys for providing bone-bonding ability

• Project/Area Number: 24650280
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Single-year Grants
• Research Field: Biomedical engineering/Biological material science
• Research Institution: Okayama University
• Principal Investigator: OSAKA Akiyoshi 岡山大学, 自然科学研究科, 名誉教授 (20033409)
• Project Period (FY): 2012-04-01 – 2014-03-31
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000); Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000); Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
• Keywords: 液相堆積法 / 酸化チタン層 / 電界紡糸 / アパタイト / 化学処理

Research Abstract

Aluminum in a 90Ti-6Al-4V titanium alloy depresses the spontaneous apatite deposition under the body environment. We applied a newly developed the liquid phase deposition not only to eliminate Al from the alloy surface but also to provide an anatase layer that leads to the apatite deposition. In addition, we employed the electrospinning technique to prepare both silica nano-tube or fibrils active to induce the apatite deposition and polymer fibril mats in which apatite was crystallized under ammonia vapor.

Research Products

• [Journal Article] Liquid phase deposited titania coating to enable in vitro apatite formation on Ti6Al4V alloy (2014)
  • Author(s): Hayakawa S, Masuda Y, Okamoto K, Shirosaki Y, Kato K, Osaka A
  • Journal Title: J Mater Sci : Mater Med Volume: 25 Issue: 2 Pages: 375-381
  • DOI: 10.1007/s10856-013-5078-z
  • Peer Reviewed
• [Presentation] Electrospinning Preparation of PVA-Ceramic Nano-Particle Composite Fiber Mats for Tissue-Engineering Applications (2014)
  • Author(s): Y. Shirosaki, S. Hayakawa, Y. Nakamura, H. Yoshihara, A. Osaka, A. Stamboulis
  • Organizer: 38th International Conference & Exposition on Advanced Ceramics & Composites (ICACC 2014)
  • Place of Presentation: Hilton Daytona Beach Resort and Ocean Center, Daytona Beach, FL, USA
  • Invited
• [Presentation] Silica Nano- fibers and nano-tubes from electrospun polymer templating (2013)
  • Author(s): Y. Shirosaki, H. Yoshihara, Y. Nakamura, S. Hayakawa, S. Chen, A. Stamboulis, N. Hanagata, A. Osaka
  • Organizer: 10th Pacific Rim Conference on Ceramic and Glass Technology
  • Place of Presentation: Hotel Coronado, San Diego, CA, USA
  • Invited
• [Presentation] Preparation of Poly(vinyl alcohol) /Hydroxyapatite Composite Nano-Fiber Mats (2013)
  • Author(s): H. Yoshihara, Y. Shirosaki, Y. Nakamura, S. Hayakawa, A. Stamboulis, A. Osaka
  • Organizer: 2nd International Symposium on Inorganic and Environmental Materials
  • Place of Presentation: the University of Rennes 1, Rennes, France
• [Presentation] Preparation of Poly(vinyl alcohol)/Hydroxyapatite Composite Nano-Fiber Mats (2013)
  • Author(s): H. Yoshihara, Y. Shirosaki, Y. Nakamura, S. Hayakawa, A. Stamboulis, A. Osaka
  • Organizer: 2nd International Symposium on Inorganic and Environmental Materials
  • Place of Presentation: The University of Rennes 1, Rennes, France
• [Book] Use of inter-fibril spaces among electrospun fibrils as ion-fixation and nano-crystallization (2014)
  • Author(s): Yuki Shirosaki, Satoshi Hayakawa, Yuri Nakamura, Hiroki Yoshihara, Akiyoshi Osaka, Artemis Stamboulis
  • Total Pages: 250
  • Publisher: Wiley
• [Book] A. Stamboulis根Use of inter-fibril spaces among electrospun fibrils as ion-fixation and nano-crystallization, Ceramic Transactions Vol. 221, Advances in Bioceramics and Biotechnologies
  • Author(s): Y. Shirosaki, S. Hayakawa, Y. Nakamura, H. Yoshihara, A. Osaka
  • Publisher: Roger Narayan and Joanna McKittrick, The American Ceramic Society, Wiley, New York.(印刷中)