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The development of the high precision navigation system of sentinel node in gastrointestinal cancer in an open MRI operating theater

Research Project

Project/Area Number 24650298
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Medical systems
Research InstitutionKobe University

Principal Investigator

KAKEJI Yoshihiro  神戸大学, 医学(系)研究科(研究院), 教授 (80284488)

Co-Investigator(Kenkyū-buntansha) TOMIKAWA Morimasa  九州大学, 大学病院, 特任准教授 (60325454)
IKEDA Tetsuo  九州大学, 大学病院, 准教授 (60585701)
NAGAO Yoshihiro  九州大学, 大学病院, 医員 (70608968)
MAEHARA Yoshihiko  九州大学, 大学院医学研究科, 教授 (80165662)
HASHIZUME Makoto  九州大学, 大学院医学研究科, 教授 (90198664)
KUMASHIRO Ryuichi  九州大学, 大学院医学研究科, 研究員 (10631591)
OKI Eiji  九州大学, 大学院医学研究科, 准教授 (70380392)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2014: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2012: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywordsコンピュータ外科学 / ナビゲーション / センチネルリンパ節 / 胃癌 / Open MRI / コンピューター外科学
Outline of Final Research Achievements

This study aims to establish the navigation system of sentinel node in gastric cancer. In an open MRI operating theater, the laparoscopic monitor clearly showed the augmented reality models of the sentinel node which is enhanced by superparamagnetic iron oxide (SPIO) injected into the gastric mucosa endoscopically. After the appropriate condition setting, laparoscopic sentinel node dissection was technically able to be performed in this navigation system. Further clinical trials may elucidate the feasibility of this navigation system.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (47 results)

All 2015 2014 2013 2012 2011 Other

All Journal Article (25 results) (of which Peer Reviewed: 21 results,  Open Access: 6 results) Presentation (21 results) (of which Invited: 5 results) Book (1 results)

  • [Journal Article] Successful laparoscopic gastric resection and safe introduction of a single-incision technique for gastric submucosal tumors located near the esophagogastric junction.2015

    • Author(s)
      Kanaji S, Nakamura T, Yamamoto M, Imanishi T, Suzuki S, Tanaka K, Kuroda D, Kakeji Y
    • Journal Title

      Surg Today

      Volume: 45 Issue: 2 Pages: 209-214

    • DOI

      10.1007/s00595-014-0940-2

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Minimally invasive image analysis of biliary-pancreatic structure for preoperative simulation.2014

    • Author(s)
      Maeda T, Konishi K, Tanouez K, Taketomi A, Shirabe K, Maehara Y, Hashizume M.
    • Journal Title

      Hepatogastroenterology

      Volume: 61 Pages: 1744-1747

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] omparison of open, laparoscopic, and hand-assisted laparoscopic devascularization of the upper stomach and splenectomy for treatment of esophageal and gastric varices: a single-center experience.2014

    • Author(s)
      Akahoshi T, Uehara H, Tomikawa M, Kawanaka H, Hashizume M, Maehara Y.
    • Journal Title

      Asian J Endosc Surg.

      Volume: 7 Issue: 2 Pages: 138-144

    • DOI

      10.1111/ases.12096

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Surgical outcomes in the newly introduced phase of intracorporeal anastomosis following laparoscopic distal gastrectomy is safe and feasible compared with established procedures of extracorporeal anastomosis2014

    • Author(s)
      Shingo Kanaji, Hitoshi Harada, Shunji Nakayama, Takashi Yasuda, Taro Oshikiri, Kentaro Kawasaki, Masashi Yamamoto, Tatsuya Imanishi, Tetsu Nakamura, Satoshi Suzuki, Kenichi Tanaka, Yasuhiro Fujino, Masahiro Tominaga, Yoshihiro Kakeji
    • Journal Title

      Surg Endosc

      Volume: 28 Pages: 1250-1255

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 本邦におけるロボット手術の導入と今後の展望2014

    • Author(s)
      家入里志, 橋爪 誠
    • Journal Title

      Journal of Japan Society of Computer Aided Surgery

      Volume: 15 Issue: 4 Pages: 319-322

    • DOI

      10.5759/jscas.15.319

    • NAID

      130003398093

    • ISSN
      1344-9486, 1884-5770
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 多元計算解剖学への新展開2014

    • Author(s)
      大内田研宙, 橋爪 誠
    • Journal Title

      INNERVISION

      Volume: 29 Pages: 63-65

    • Related Report
      2014 Annual Research Report
  • [Journal Article] Extent of arterial tumor enhancement measured with preoperative MDCT gastrography is a prognostic factor in advanced gastric cancer after curative resection.2013

    • Author(s)
      Komori M, Asayama Y, Fujita N, Hiraka K, Tsurumaru D, Kakeji Y, Honda H.
    • Journal Title

      AJR Am J Roentgenol.

      Volume: 201(2) Issue: 2 Pages: 253-261

    • DOI

      10.2214/ajr.12.9206

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Surgical outcomes in the newly introduced phase of intracorporeal anastomosis following laparoscopic distal gastrectomy is safe and feasible compared with established procedures of extracorporeal anastomosis.2013

    • Author(s)
      Kanaji S, Harada H, Nakayama S, Yasuda T, Oshikiri T, Kawasaki K, Yamamoto M, Imanishi T, Nakamura T, Suzuki S, Tanaka K, Fujino Y, Tominaga M, Kakeji Y.
    • Journal Title

      Surg Endosc.

      Volume: -

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Progression from laparoscopic-assisted to totally laparoscopic distal gastrectomy: comparison of circular stapler (i-DST) and linear stapler (BBT) for intracorporeal anastomosis.2013

    • Author(s)
      Ikeda T., Kawano H., Hisamatsu Y., Ando K., Saeki H., Oki E., Ohga T., Kakeji Y., Tsujitani S., Kohnoe S., Maehara Y.
    • Journal Title

      Surg Endosc

      Volume: 27(1) Issue: 1 Pages: 325-332

    • DOI

      10.1007/s00464-012-2433-y

    • Related Report
      2013 Research-status Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Total Laparoscopic Distal Gastrectomy for Elderly Patients with Gastric Cancer.2013

    • Author(s)
      Oki E., Sakaguchi Y., Ohgaki K., Saeki H., Ikegami T., Minami K., Yamashita Y., Toh Y., Soejima Y., Ando K., Mimori K., Watanabe M., Sugimachi K., Uchiyama H., Yoshizumi T., Kawanaka H., Morita M., Ikeda T., Maehara Y.
    • Journal Title

      Fukuoka Acta Medica

      Volume: 104(9) Pages: 290-298

    • NAID

      120005372094

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Image-guided laparoscopic surgery in an open MRI operating theater.2013

    • Author(s)
      Tsutsumi N, Tomikawa M, Uemura M, Akahoshi T, Nagao Y, Konishi K, Ieiri S, Hong J, Maehara Y, Hashizume M.
    • Journal Title

      Surg Endosc.

      Volume: 27(6) Issue: 6 Pages: 2178-84

    • DOI

      10.1007/s00464-012-2737-y

    • Related Report
      2013 Research-status Report
  • [Journal Article] Robotic surgery for cancer.2013

    • Author(s)
      Ohuchida K, Hashizume M.
    • Journal Title

      Cancer J.

      Volume: 19(2) Issue: 2 Pages: 130-2

    • DOI

      10.1097/ppo.0b013e31828da251

    • Related Report
      2013 Research-status Report
  • [Journal Article] An augmented reality navigation system for pediatric oncologic surgery based on preoperative CT and MRI images.2013

    • Author(s)
      Souzaki R, Ieiri S, Uemura M, Ohuchida K, Tomikawa M, Kinoshita Y, Koga Y, Suminoe A, Kohashi K, Oda Y, Hara T, Hashizume M, Taguchi T.
    • Journal Title

      J Pediatr Surg.

      Volume: 48 Issue: 12 Pages: 2479-83

    • DOI

      10.1016/j.jpedsurg.2013.08.025

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Formulation of wire control mechanism for surgical robot to create virtual reality environment aimed at conducting surgery inside the body.2013

    • Author(s)
      Suzuki N, Hattori A, Ieiri S, Tomikawa M, Kenmotsu H, Hashizume M.
    • Journal Title

      Stud Health Technol Inform

      Volume: 184 Pages: 424-30

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Pure laparoscopic hepatectomy in semiprone position for right hepatic major resection.2013

    • Author(s)
      Ikeda T, Mano Y, Morita K, Hashimoto N, Kayashima H, Masuda A, Ikegami T, Yoshizumi T, Shirabe K, Maehara Y.
    • Journal Title

      J Hepatobiliary Pancreat Sci.

      Volume: 20(2) Issue: 2 Pages: 145-50

    • DOI

      10.1007/s00534-012-0558-y

    • NAID

      10031168204

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Lymph node metastasis from cancer of the esophagogastric junction, and determination of the appropriate nodal dissection2012

    • Author(s)
      Kakeji Y, Yamamoto M, Ito S, Sugiyama M, Egashira A, Saeki H, Morita M, Sakaguchi Y, Toh Y, Maehara Y
    • Journal Title

      Surg Today

      Volume: 42 Issue: 4 Pages: 351-358

    • DOI

      10.1007/s00595-011-0114-4

    • NAID

      10030546298

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Quality of life after laparoscopy-assisted pylorus-preserving gastrectomy: an evaluation using a questionnaire mailed to the patients.2012

    • Author(s)
      Tomikawa M, Korenaga D, Akahoshi T, Kohshi K, Sugimachi K, Nagao Y, Tsutsumi N, Takenaka K, Kakeji Y, Hashizume M, Maehara Y.
    • Journal Title

      Surg Today

      Volume: 42(7): Issue: 7 Pages: 625-632

    • DOI

      10.1007/s00595-012-0182-0

    • NAID

      10030788161

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Esophageal replacement by colon interposition with microvascular surgery for the patients with thoracic esophageal cancer2012

    • Journal Title

      The utility with super drainage. Dis Esophagus

      Volume: 26 Issue: 1 Pages: 50-56

    • DOI

      10.1111/j.1442-2050.2012.01327.x

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Patterns and time of recurrence after complete resection of esophageal cancer2012

    • Author(s)
      Sugiyama M, Morita M, Yoshida R, 他8名
    • Journal Title

      Surg Today

      Volume: 42 Issue: 8 Pages: 752-758

    • DOI

      10.1007/s00595-012-0133-9

    • NAID

      10030949064

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Rigid and flexible endoscopic rendezvous in spatium peritonealis may be an effective tactic for laparoscopic megasplenectomy: significant implications for pure natural orifice translumenal endoscopic surgery.2012

    • Author(s)
      Tomikawa M, Akahoshi T, Kinjo N, Uehara H, Hashimoto N, Nagao Y, Kamori M, Kumashiro R, Maehara Y, Hashizume M.
    • Journal Title

      Surgical Endoscopy

      Volume: 26(12) Issue: 12 Pages: 3573-9

    • DOI

      10.1007/s00464-012-2369-2

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] [Robotic surgery for cancer treatment].2012

    • Author(s)
      Oouchida K, Ieiri S, Kenmotsu H, Tomikawa M, Hashizume M.
    • Journal Title

      Gan To Kagaku Ryoho

      Volume: 39(1) Pages: 1-7

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Augmented reality navigation system for laparoscopic splenectomy in children based on preoperative CT image using optical tracking device2012

    • Author(s)
      Ieiri S, Uemura M, Konishi K, Souzaki R, Nagao Y, Hashizume M, Taguchi T.
    • Journal Title

      Pediatr Surg Int

      Volume: 28 Issue: 4 Pages: 341-346

    • DOI

      10.1007/s00383-011-3034-x

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Clinical Application of the Diagnostic and Therapeutic Model Assisted by the Computational Anatomy2011

    • Author(s)
      橋爪 誠,富川盛雅
    • Journal Title

      Medical Imaging Technology

      Volume: 29 Issue: 3 Pages: 143-148

    • DOI

      10.11409/mit.29.143

    • NAID

      130000886611

    • ISSN
      0288-450X, 2185-3193
    • Related Report
      2014 Annual Research Report
    • Open Access
  • [Journal Article] Laparoscopic resection for gastrointestinal stromal tumors in the stomach2011

    • Author(s)
      Kakeji Y., et al
    • Journal Title

      Sugery Today online

      Volume: (Epub ahead of print) Issue: 6 Pages: 554-558

    • DOI

      10.1007/s00595-011-0072-x

    • NAID

      10030622072

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Totally laparoscopic colectomy with intracorporeal anastomosis achieved using a laparoscopic linear stapler : experience of a single institute2011

    • Author(s)
      Ikeda T., et al
    • Journal Title

      Surgery Today

      Volume: 42 Issue: 1 Pages: 41-5

    • DOI

      10.1007/s00595-011-0003-x

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Presentation] 最新の3Dシステムと手術支援ロボットシステムの動向 ~内視鏡外科を事例として超精密加工技術に期待するもの~2014

    • Author(s)
      橋爪 誠
    • Organizer
      将来加工技術 第136委員会 創設50周年記念シンポジウム
    • Place of Presentation
      京都
    • Year and Date
      2014-11-28
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] インテリジェント手術支援ロボットシステムの開発2014

    • Author(s)
      橋爪 誠
    • Organizer
      第28回日本泌尿器内視鏡学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2014-11-26 – 2014-11-28
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 生体医工学・医用画像解析に基づいた、曲げて、捻って内部構造の変化がはっきり見え、電気メスで切れる、肝臓手術ナビゲーションシステムの検討2014

    • Author(s)
      池田哲夫、吉田佳弘、今井大祐、松本佳大、別城悠樹、赤星朋比古、木村光一、中川原英和、播本憲史、伊藤心二、山下洋市、池上徹、吉住朋晴、橋爪誠
    • Organizer
      第76回日本臨床外科学会
    • Place of Presentation
      福島
    • Year and Date
      2014-11-21
    • Related Report
      2014 Annual Research Report
  • [Presentation] 画像誘導装置の現状と今後の展望2014

    • Author(s)
      赤星 朋比古、富川 盛雅、池田 哲夫、橋爪 誠
    • Organizer
      第27回日本内視鏡外科学会総会
    • Place of Presentation
      岩手
    • Year and Date
      2014-10-02 – 2014-10-04
    • Related Report
      2014 Annual Research Report
  • [Presentation] 消化器・一般外科領域におけるナビゲーションサージェリーの現状と今後の展望2014

    • Author(s)
      富川 盛雅、植村 宗則、赤星 朋比古、内山 秀昭、遠藤 和也、是永 大輔、竹中 賢治、橋爪 誠
    • Organizer
      第52回日本癌治療学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2014-08-28 – 2014-08-30
    • Related Report
      2014 Annual Research Report
  • [Presentation] 胃癌における機能温存手術2014

    • Author(s)
      鈴木 知志、金治 新悟、中村 哲、山本 将士、金光 聖哲、山下 公大、今西 達也、角 泰雄、田中 賢一、掛地 吉弘
    • Organizer
      第52回日本癌治療学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2014-08-28 – 2014-08-30
    • Related Report
      2014 Annual Research Report
  • [Presentation] 手術支援ナビゲーションシステムの開発と臨床応用における課題2014

    • Author(s)
      橋爪 誠
    • Organizer
      第102回日本泌尿器科学会総会
    • Place of Presentation
      神戸
    • Year and Date
      2014-04-24 – 2014-04-27
    • Related Report
      2014 Annual Research Report
  • [Presentation] 胃がんに対する3D手術とロボット支援手術の経験2014

    • Author(s)
      大内田研宙,永井英司,仲田興平,山田大輔,中村勝也,清水周次,橋爪 誠,田中雅夫:
    • Organizer
      第114回日本外科学会定期学術集会
    • Place of Presentation
      京都
    • Year and Date
      2014-04-03 – 2014-04-05
    • Related Report
      2014 Annual Research Report
  • [Presentation] 胃癌腹膜播腫に対する治療と展開2013

    • Author(s)
      掛地 吉弘
    • Organizer
      第113回日本外科学会定期学術集会
    • Place of Presentation
      福岡
    • Related Report
      2013 Research-status Report
  • [Presentation] 外科療法2013

    • Author(s)
      掛地 吉弘
    • Organizer
      第11回日本臨床腫瘍学会学術集会
    • Place of Presentation
      宮崎
    • Related Report
      2013 Research-status Report
  • [Presentation] 腹腔鏡下前方切除術におけるリニアステープラーを用いた新しい吻合法の開発2013

    • Author(s)
      沖  英次、池田 哲夫、安藤 幸滋、井田  智、 木村 和恵、佐伯 浩司、森田  勝、楠本 哲也、 前原 喜彦
    • Organizer
      第113回日本外科学会定期学術集会
    • Place of Presentation
      福岡
    • Related Report
      2013 Research-status Report
  • [Presentation] 胃・大腸癌組織におけるCXCL12/CXCR4発現による浸潤転移の分子機序とその制御2012

    • Author(s)
      掛地 吉弘、増田 隆伸、安藤 幸滋、佐伯 浩司、沖 英次、大賀 丈史、辻谷 俊一、鴻江 俊冶、米満 吉和、前原 喜彦
    • Organizer
      第67回日本消化器外科学会
    • Place of Presentation
      富山国際会議場
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] コンピューター診断支援システムNewVESを応用した消化器外科領域の治療シミュレーション2012

    • Author(s)
      富川 盛雅、小田 昌宏、神代 竜一、赤星 朋比古、橋本 直隆、長尾 吉泰、掛地 吉弘、森 健策、前原 喜彦、橋爪 誠
    • Organizer
      第67回日本消化器外科学会
    • Place of Presentation
      富山国際会議場
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] 完全腹腔鏡下幽門側胃切除における三角吻合(Book Binding法)の工夫2012

    • Author(s)
      安藤 幸滋、佐伯 浩司、池田 哲夫、神代 竜一、沖 英次、大賀 丈史、掛地 吉弘、辻谷 俊一、鴻江 俊治、前川 喜彦
    • Organizer
      第67回日本消化器外科学会
    • Place of Presentation
      富山国際会議場
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] OMRI装置を利用した広範囲レドックスイメージングを実現するESR局所コイルロボット.

    • Author(s)
      豊田和孝, 村田正治, 橋爪 誠
    • Organizer
      第51回 日本生体医工学会大会
    • Place of Presentation
      福岡
    • Related Report
      2012 Research-status Report
  • [Presentation] 手術支援ロボットの開発

    • Author(s)
      橋爪 誠
    • Organizer
      第112回日本外科学会定期学術集会
    • Place of Presentation
      千葉
    • Related Report
      2012 Research-status Report
  • [Presentation] 九州大学病院におけるロボット手術の普及へ向けた取り組み-ロボット外科医の教育と新規国産手術支援ロボットの研究開発-.

    • Author(s)
      家入里志, 宗崎良太, 長尾吉泰, 大内田研宙, 赤星朋比古, 大平 猛, 富川盛雅, 田口智章, 橋爪 誠
    • Organizer
      第112回日本外科学会定期学術集会
    • Place of Presentation
      千葉
    • Related Report
      2012 Research-status Report
  • [Presentation] 医科におけるロボット手術の最前線.

    • Author(s)
      橋爪 誠
    • Organizer
      第22回日本顎変形症学会総会
    • Place of Presentation
      福岡
    • Related Report
      2012 Research-status Report
  • [Presentation] Recent advances in robotic surgery.

    • Author(s)
      Hashizume M
    • Organizer
      The Korean Journal of Endourology
    • Place of Presentation
      Korea
    • Related Report
      2012 Research-status Report
  • [Presentation] A newly-developed novel konjak Complex Marker (KCM) for MRI-guided intra-abdominal surgery.

    • Author(s)
      徐 号, 橋爪 誠
    • Organizer
      第51回 日本生体医工学会大会
    • Place of Presentation
      福岡
    • Related Report
      2012 Research-status Report
  • [Presentation] MRIガイド腹腔内臓器手術に対応する生体内用蒟蒻コンプレックスマーカーの開発

    • Author(s)
      徐 号, 富川盛雅, 植村宗則, 家入里志, 橋爪 誠
    • Organizer
      第51回 日本生体医工学会大会
    • Place of Presentation
      福岡
    • Related Report
      2012 Research-status Report
  • [Book] Patient Surveillance After Cancer Treatment, Current Clinical Oncology.2013

    • Author(s)
      Kakeji Y, Morita M, Maehara Y. Stomach Carcinoma Surveillance Counterpoint: Japan. Johnson FE, et al.
    • Total Pages
      538
    • Publisher
      Springer Science + Business Media
    • Related Report
      2013 Research-status Report

URL: 

Published: 2013-05-31   Modified: 2019-07-29  

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