| Project/Area Number |
24650300
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Medical systems
|
|---|
| Research Institution | Tokyo Denki University |
|---|
Principal Investigator |
UENO Akinori 東京電機大学, 工学部, 教授 (20318158)
|
|---|
| Project Period (FY) |
2012-04-01 – 2014-03-31
|
| Project Status |
Completed (Fiscal Year 2013)
|
| Budget Amount *help |
¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
|
|---|
| Keywords | 検査・診断システム / 非侵襲計測 / 自律神経電気活動 / 筋交感神経活動 / Laplacian電極 / 高入力インピーダンス / Wavelet denoising / 自律神経 / ラプラシアン電極 / 筋交感神経 / 神経工学 |
|---|
| Research Abstract |
A prototype of concentric bipolar active (CBA) electrode with ultra-high input impedance was made. The CBA electrode, combined with a separately developed bio-amplifier with high common mode rejection ratio (CMRR), was investigated to measure muscle sympathetic nerve activity (MSNA) noninvasively from sciatic nerve at posterior region of knee. Simultaneous measurement of the proposed approach and invasive microneurography (MNG) was conducted. While intermittent MSNA bursts were observed clearly in the MNG recording, burst-like spike potentials in the recording of the proposed method were observed only after applying a modified Wavelet-based denoising. However, both activated periods were almost the same, and both peak values of the rectified and integrated bursts correlated each other.
|
