Project/Area Number |
24650303
|
Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
Allocation Type | Multi-year Fund |
Research Field |
Medical systems
|
Research Institution | Fukuoka University |
Principal Investigator |
|
Co-Investigator(Kenkyū-buntansha) |
TACHIBANA Katsuro 福岡大学, 医学部, 教授 (40271605)
小川 皓一 福岡大学, 医学部, 准教授 (60078780)
|
Co-Investigator(Renkei-kenkyūsha) |
OGAWA Koichi 福岡大学, 医学部, 准教授 (60078780)
|
Project Period (FY) |
2012-04-01 – 2015-03-31
|
Project Status |
Completed (Fiscal Year 2014)
|
Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2014: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2012: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
|
Keywords | apoptosis / 電磁波作用 / 電磁場 / 白内障 / 抗酸化作用 / 音響化学療法 / 光線力学的治療 / 超音波 / 電磁波 / アポトーシス / ミトコンドリア / 電子伝達系 / 細胞分裂 / 細胞増殖 / 分化誘導 / 神経細胞 |
Outline of Final Research Achievements |
FFT analysis demonstrated that the electromagnetic waves that induced apoptosis in neurons were complex waveforms with various high frequencies.It was also confirmed that the mechanism for electromagnetic wave apoptosis induction was caused by damage of intracellular organelles. Furthermore, the fact that an experiment using porcine eyes proved that electromagnetic waves cause collapse of the crystalline lens cellular structure, leading to cataracts, revealed possibilities for finding a method of preventing cataracts in modern society, in which many electromagnetic waves abound. We also analyzed electromagnetic wave sensitivity in a comparison of healthy and cancer cells. Electromagnetic radiation impeded cell proliferation in healthy cells but actually increased cell proliferation in cancer cells. This suggests that the intracellular organelles of cancer cells have strong antioxidant action, and this finding could contribute to cancer treatment in the future.
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