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Neuroplasticity induced by transcranial direct current stimulation. -TSM/MEG/NIRS study-

Research Project

Project/Area Number 24650335
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Rehabilitation science/Welfare engineering
Research InstitutionNiigata University of Health and Welfare

Principal Investigator

YAMAMOTO Noriaki  新潟医療福祉大学, その他部局等, その他 (30445902)

Co-Investigator(Kenkyū-buntansha) ONISHI Hideaki  新潟医療福祉大学, 医療技術学部, 教授 (90339953)
TAMAKI Hiroyuki  新潟医療福祉大学, 医療技術学部, 教授 (40253926)
TSUBAKI Atsuhiro  新潟医療福祉大学, 医療技術学部, 准教授 (50410262)
SUZUKI Makoto  北里大学, 医療衛生学部, 教授 (80554302)
SATO Daisuke  新潟医療福祉大学, 健康科学部, 講師 (60544393)
YAMASHIRO Koya  新潟医療福祉大学, 健康科学部, 講師 (20570782)
SUGAWARA Kazuhiro  新潟医療福祉大学, 医療技術学部, 助教 (10571664)
桐本 光  新潟医療福祉大学, 医療技術学部, 准教授 (40406260)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords経頭蓋直流電流刺激 / tDCS / 近赤外線分光イメージング / 脳磁図 / 体性感覚誘発磁界 / NIRS / MEG / 近赤外線分光法 / SEF / 経頭蓋磁気刺激 / 運動誘発電位 / MEP / TMS
Outline of Final Research Achievements

In the present study, we investigated whether anodal transcranial direct current stimulation (tDCS) application to motor cortex is affected differential of current intensity or electrode position. The anodal electrode was placed on the left scalp over the primary motor area (M1). The cathodal electrode was placed above the right scalp over the orbit or right M1 (unilateral tDCS and bilateral tDCS, respectively). All subjects underwent the following four interventions: unilateral tDCS or bilateral tDCS delivered with 1 mA and 2 mA for 10 min. Motor evoked potentials (MEPs) were recorded before and 2 min and 10 min after intervention. As results, under the bilateral_2 mA condition, the MEP at 2 min and 10 min after intervention were significantly increased compared with those before the intervention. Under the other conditions, the MEP remained unchanged. These results demonstrated that anodal tDCS is highly affected differential of current intensity or electrode position.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (9 results)

All 2015 2014 2013 2012 Other

All Journal Article (3 results) (of which Peer Reviewed: 3 results,  Acknowledgement Compliant: 1 results) Presentation (5 results) (of which Invited: 1 results) Remarks (1 results)

  • [Journal Article] 経頭蓋直流電流刺激の効果的な介入方法の検討-電極貼付部位および電流強度の影響-2015

    • Author(s)
      宮口翔太,大西秀明,小島翔,菅原和広,桐本光,田巻弘之,山本智章
    • Journal Title

      理学療法学

      Volume: 印刷中

    • NAID

      110009970961

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] The effect of anodal transcranial direct current stimulation over the primary motor or somatosensory cortices on somatosensory evoked magnetic fields2014

    • Author(s)
      Sugawara K, Onishi H, Yamashiro K, Kojima S, Miyaguchi S, Kirimoto H, Tsubaki A, Tamaki H, Shirozu H, Kameyama S.
    • Journal Title

      Clinical Neurophysiology

      Volume: (In-press)

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Corticomotor excitability induced by anodal transcranial direct current stimulation with and without non-exhaustive movement.2013

    • Author(s)
      Miyaguchi S, Onishi H, Kojima S, Sugawara K, Tsubaki A, Kirimoto H, Tamaki H, Yamamoto N.
    • Journal Title

      Brain Research

      Volume: 1529 Pages: 83-91

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] Effect of transcranial direct current stimulation over the primary motor cortex on cerebral blood flow: A time course study using near-infrared spectroscopy2014

    • Author(s)
      Takai H, Tsubaki A, SUgawara K, Miyaguchi S, Oyanagi K, Matsumoto T, Onishi H, Yamamoto N
    • Organizer
      The 42rd Annual Meeting of the International Society on Oxygen Transport to Tissue (ISOTT 2014)
    • Place of Presentation
      London
    • Year and Date
      2014-06-28 – 2014-07-03
    • Related Report
      2014 Annual Research Report
  • [Presentation] 一次運動野領域への経頭蓋直流電流刺激が電極直下および同側頭蓋内血流動態に与える影響2014

    • Author(s)
      高井遥菜,椿淳裕,菅原和広,宮口翔太,小柳圭一,松本卓也, 大西秀明,山本智章
    • Organizer
      第49回日本理学療法学術大会
    • Place of Presentation
      神奈川
    • Year and Date
      2014-05-30 – 2014-06-01
    • Related Report
      2014 Annual Research Report
  • [Presentation] 一次体性感覚野への陰極経頭蓋直流電流刺激が短潜時および長潜時求心性抑制に及ぼす影響2013

    • Author(s)
      小島 翔,宮口翔太,菅原和広,桐本 光,田巻弘之,大西秀明.
    • Organizer
      第48回日本理学療法学会学術大会
    • Place of Presentation
      名古屋市(愛知県)
    • Related Report
      2013 Research-status Report
  • [Presentation] 中枢神経障害に対する理学療法2013

    • Author(s)
      大西秀明
    • Organizer
      第28回日本理学療法士協会全国学術研修大会
    • Place of Presentation
      静岡市(静岡県)
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] 経頭蓋直流電気刺激が皮質運動野興奮性に及ぼす影響-電極貼付部位と電流強度の影響-2012

    • Author(s)
      宮口翔太,大西秀明,小島 翔,菅原和広,桐本 光,田巻弘之,山本智章.
    • Organizer
      第42回日本臨床神経生理学会学術大会
    • Place of Presentation
      東京
    • Related Report
      2012 Research-status Report
  • [Remarks] 運動機能医科学研究所

    • URL

      http://www.ihmms.jp/

    • Related Report
      2013 Research-status Report

URL: 

Published: 2013-05-31   Modified: 2019-07-29  

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