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Development of the new treatment for the muscle injury using ultrasonic stimulation

Research Project

Project/Area Number 24650337
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeSingle-year Grants
Research Field Rehabilitation science/Welfare engineering
Research InstitutionChubu University

Principal Investigator

MIYAMOTO Yasunori  中部大学, 医療技術実習センター, 講師 (00612665)

Co-Investigator(Kenkyū-buntansha) AGATA Nobuhide  常葉大学, 保健医療学部, 助教 (00549313)
Project Period (FY) 2012-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywordsリハビリテーション / 発生・分化 / ラット / 細胞・組織 / 理学療法学 / 筋損傷
Research Abstract

This research verified ultrasonic stimulation can promote recovery from muscle damage. We produced the model of injured rats is caused by eccentric contraction of anterior tibial muscle. The anterior tibial muscle was pulsed 10 minutes by ultrasonic stimulation. Functional evaluation, histological evaluation, and biochemical evaluation were used for evaluation of recovery from muscle damage.
As a result, ultrasonic stimulation added 2 hours after eccentric contraction is effective in promoting recovery from injury. Moreover, the expression level of MyoD and Myogenin protein which are an active index of a satellite cell increases by ultrasonic stimulation. The examination suggested that an ultrasonic stimulus becomes a new treatment for the promotion of recovery from muscle damage.

Report

(3 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • Research Products

    (4 results)

All 2013 Other

All Presentation (4 results)

  • [Presentation] Ultrasonic stimulation to promote recovery from muscle injury2013

    • Author(s)
      Atsushi Shibata, Tomonori Mori, Nobuhide Agata, Yasunori Miyamoto, Masumi Inoue-Miyazu, Keisuke Kawakami
    • Organizer
      WCPT-AWP&ACPT Congress 2013
    • Place of Presentation
      Nan Shan Education and Training Center, Taichung, Taiwan
    • Year and Date
      2013-09-08
    • Related Report
      2013 Final Research Report
  • [Presentation] 超音波刺激が筋損傷の回復過程に与える影響2013

    • Author(s)
      柴田篤志、森友洋、縣信秀、宮本靖義、宮津真寿美、河上敬介
    • Organizer
      第48回日本理学療法学術大会
    • Place of Presentation
      名古屋国際セ会議場,名古屋,愛知
    • Year and Date
      2013-05-26
    • Related Report
      2013 Final Research Report
  • [Presentation] Ultrasonic stimulation to promote recovery from muscle injury

    • Author(s)
      Atsushi Shibata, Tomonori Mori, Nobuhide Agata, Yasunori Miyamoto, Masumi Inoue-Miyazu, Keisuke Kawakami
    • Organizer
      WCPT-AWP & ACPT Congress 2013
    • Place of Presentation
      Nan Shan Education & Training Center
    • Related Report
      2013 Annual Research Report
  • [Presentation] 超音波刺激が筋損傷の回復過程に与える影響

    • Author(s)
      柴田篤志、森友洋、縣信秀、宮本靖義、宮津真寿美、河上敬介
    • Organizer
      第48回日本理学療法学術大会
    • Place of Presentation
      名古屋国際会議場
    • Related Report
      2013 Annual Research Report

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Published: 2013-05-31   Modified: 2019-07-29  

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