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Spatial heterogeneity of anaerobic threshold in exercsing muscles

Research Project

Project/Area Number 24650401
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeSingle-year Grants
Research Field Sports science
Research InstitutionKobe Design University

Principal Investigator

KOGA Shunsaku  神戸芸術工科大学, デザイン学部, 教授 (50125712)

Project Period (FY) 2012-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Keywords活動筋の酸素供給と消費 / 複数部位ATの推定 / 筋線維動員パターン / 脱酸素化ヘモグロビン / 活動筋ATの空間分布 / VO2 slow component / 活動筋の無酸素性作業閾値の空間不均一性
Research Abstract

Investigation of the relative matching of O2 delivery (Qo2)-O2 utilization (Vo2) within and among muscles is crucial for resolving the mechanistic bases for vascular and metabolic control and O2 deficit at the onset of exercise. Muscle oxygenation/deoxygenation reflects the balance between Qo2 and Vo2, i.e., Qo2/Vo2 ratio (or Vo2/Qo2 as deoxygenation). Thus, the profile of spatial heterogeneity of muscle deoxygenation, for example, following the onset of exercise can provide important information regarding the adequacy of the vascular response and the O2 pressures essential for driving blood-muscle O2 flux.

Report

(3 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • Research Products

    (16 results)

All 2014 2013 2012 Other

All Journal Article (6 results) (of which Peer Reviewed: 6 results,  Acknowledgement Compliant: 1 results) Presentation (5 results) Book (2 results) Remarks (3 results)

  • [Journal Article] Dynamic heterogeneity of exercising muscle blood flow and O_2 utilization2014

    • Author(s)
      Koga S, Rossiter HB, Heinonen I, Musch TI, Poole C
    • Journal Title

      Med Sci Sports Exer

      Volume: 46巻 Pages: 860-876

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Dynamic heterogeneity of exercising muscle blood flow and O2 utilization.2014

    • Author(s)
      Koga S, Rossiter HB, Heinonen I, Musch TI, Poole DC.
    • Journal Title

      Med Sci Sports Exer

      Volume: 46 Issue: 5 Pages: 860-876

    • DOI

      10.1249/mss.0000000000000178

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Increasing temperature speeds intracellular PO_2 kinetics during contractions in single Xenopus skeletal muscle fibers2013

    • Author(s)
      Koga S, Wüst RC, Walsh B, Kindig CA, Rossiter HB, Hogan MC
    • Journal Title

      Am J Physiol Regul Integr Comp Physiol

      Volume: 304巻 Pages: 59-66

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Slowed oxygen uptake kinetics in hypoxia correlate with deoxygenation2013

    • Author(s)
      Bowen TS, Rossiter HB, Benson AP, Amano T, Kondo N, Kowalchuk JM, Koga S
    • Journal Title

      Exp Physiol

      Volume: 98巻 Pages: 1585-1596

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Slowed oxygen uptake kinetics in hypoxia correlate with the transient peak and reduced spatial distribution of absolute skeletal muscle deoxygenation.2013

    • Author(s)
      Bowen TS, Rossiter HB, Benson AP, Amano T, Kondo N, Kowalchuk JM, Koga S.
    • Journal Title

      Exp Physiol

      Volume: 98 Issue: 11 Pages: 1585-1596

    • DOI

      10.1113/expphysiol.2013.073270

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Increasing temperature speeds intracellular PO2 kinetics during contractions in single Xenopus skeletal muscle fibers2013

    • Author(s)
      Koga S, Wust RC, Walsh B, Kindig CA, Rossiter HB, Hogan MC
    • Journal Title

      Am J Physiol Regul Integr Comp Physiol

      Volume: 304 Issue: 1 Pages: 59-66

    • DOI

      10.1152/ajpregu.00337.2012

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Presentation] 非定常状態における活動筋の酸素供給と消費の不均一性2012

    • Author(s)
      古賀俊策
    • Organizer
      呼吸研究会シンポジウム
    • Place of Presentation
      岐阜市
    • Year and Date
      2012-09-13
    • Related Report
      2013 Final Research Report
  • [Presentation] Dynamic heterogeneity of exercising muscle O_2 exchange2012

    • Author(s)
      Koga S
    • Organizer
      ACSM Annual Meetingアメリカスポーツ医学会シンポジウム
    • Place of Presentation
      サンフランシスコ市
    • Year and Date
      2012-06-01
    • Related Report
      2013 Final Research Report
  • [Presentation] Brachial artery blood flow during sinusoidal leg cycling exercise: effects of the period

    • Author(s)
      Fukuba Y, A Kondo, Watanabe S, Kikugawa Y, Endo M, Miura A, Hayashi N, Fukuoka Y, Koga S.
    • Organizer
      American College of Sports Medicine Meeting
    • Place of Presentation
      Indianapolis (USA)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 非定常状態における活動筋の酸素供給と消費の不均一性

    • Author(s)
      古賀 俊策
    • Organizer
      呼吸研究会シンポジウム
    • Place of Presentation
      岐阜市
    • Related Report
      2012 Research-status Report
  • [Presentation] Dynamic heterogeneity of exercising muscle O2 exchange 活動筋酸素交換の動的不均一性

    • Author(s)
      古賀 俊策
    • Organizer
      ACSM Annual Meeting アメリカスポーツ医学会シンポジウム
    • Place of Presentation
      San Francisco
    • Related Report
      2012 Research-status Report
  • [Book] 活動筋の酸素動態不均一性:身体運動と呼吸・循環機能2012

    • Author(s)
      古賀俊策(宮村實晴(編))
    • Publisher
      真興交易医書出版部
    • Related Report
      2013 Final Research Report
  • [Book] 活動筋の酸素動態不均一性:身体運動と呼吸・循環機能 宮村實晴(編)2012

    • Author(s)
      古賀 俊策
    • Total Pages
      344
    • Publisher
      真興交易医書出版部
    • Related Report
      2012 Research-status Report
  • [Remarks]

    • URL

      http://www.kobe-du.ac.jp/faculty_member/s-koga/

    • Related Report
      2013 Final Research Report
  • [Remarks] 神戸芸術工科大学 教員紹介

    • URL

      http://www.kobe-du.ac.jp/faculty_member/s-koga/

    • Related Report
      2013 Annual Research Report
  • [Remarks] 神戸芸術工科大学・大学院芸術工学研究科 教員サイト

    • URL

      http://www.kobe-du.ac.jp/faculty_member/s-koga/

    • Related Report
      2012 Research-status Report

URL: 

Published: 2013-05-31   Modified: 2019-07-29  

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