| Project/Area Number |
24650415
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Applied health science
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| Research Institution | Tohoku University |
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Principal Investigator |
YOSHIZAWA Makoto 東北大学, サイバーサイエンスセンター, 教授 (60166931)
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| Co-Investigator(Renkei-kenkyūsha) |
HOMMA Noriyasu 東北大学, 大学院医学系研究科, 教授 (30282023)
SUGITA Norihiro 東北大学, 大学院工学研究科, 准教授 (90396458)
YAMBE Tomoyuki 東北大学, 加齢医学研究所, 教授 (70241578)
TANAKA Akira 福島大学, 共生システム理工学類, 教授 (10323057)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2014: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2012: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 自律神経 / 循環制御系 / 脈波伝搬時間 / 脈波 / αインデックス / CVRR / μPA / 加齢変化 / 自律神経機能 / 光電容積脈波 / 血圧反射機能 / ρmax / 相互相関係数 / コヒーレンス関数 / 伝達関数 |
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| Outline of Final Research Achievements |
This study aimed at developing an estimation system of the baroreflex function, which can be used in daily life using the photoplethysmogram based on dynamics between blood pressure and heart rate.
First, it was revealed that two indices, i.e., CVRR defined as the standard deviation of heart rate normalized by its mean value and μPA defined as the natural logarithm of the ratio of low frequency components to high frequency components of the pulse wave amplitude, have high discrimination ability and high reproducibility. Secondly, it was shown that a subject’s age can be estimated with these two indices with the correlation coefficient of 0.774. Finally, it was suggested that the baroreflex function can be estimated by processing the video images of a human body taken with an ordinary video camera.
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