| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
The purpose of this study was to examine the legacy effect of food intake and exercise in childhood on the gene expression profiles of skeletal muscle, liver, and fat tissue in adulthood by using mice.
Our results suggested that the high fat diet and exercise in childhood might produce the legacy effect on the gene expression profiles of skeletal muscle, liver, and fat tissue in Adulthood even though the mice have almost same body weight and life style. And some of the gene expressions in adulthood also have the epigenetics changes produced by DNA methylation on the promoter regions after exercise in childhood.
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