Establishment of evaluation criteria for food safety by AGE measurement
Project/Area Number |
24650482
|
Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
Allocation Type | Multi-year Fund |
Research Field |
Eating habits, studies on eating habits
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Research Institution | Tokai University |
Principal Investigator |
NAGAI Ryoji 東海大学, 農学部, 准教授 (20315295)
|
Co-Investigator(Kenkyū-buntansha) |
KAWAKAMI Shigeki 大阪大学, 産業科学研究所, 特任准教授 (90432509)
|
Project Period (FY) |
2012-04-01 – 2015-03-31
|
Project Status |
Completed (Fiscal Year 2014)
|
Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
Keywords | メイラード反応 / 食品 / 安全性 / 栄養学 / 食品保存 / AGEs / 褐色色素 / 加熱 / 褐変反応 / メラノイジン / 味噌 |
Outline of Final Research Achievements |
Recent studies demonstrate that Advanced Glycation End-products (AGEs)/melanoidins generated from the Maillard reaction in foods are associated with the worsening of diabetes. Those reports raise questions about the risk for intake of Japanese traditional foods such as Miso and Soy source. In the present study, we developed the assay system for AGEs content in Miso by instrumental analysis and immunochemical method. Accurate measurement of AGEs content in Miso may decrease the harmful rumor.
|
Report
(4 results)
Research Products
(28 results)
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[Journal Article] Ovalbumin modified with pyrraline, a Maillard reaction product, shows enhanced T-cell immunogenicity.2014
Author(s)
(130) Heilmann M, Wellner A, Gadermaier G, Ilchmann A, Briza P, Krause M, Nagai R,Burgdorf S, Scheurer S, Vieths S, Henle T, Toda M.
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Journal Title
J Biol Chem.
Volume: 289(11)
Issue: 11
Pages: 7919-7928
DOI
Related Report
Peer Reviewed
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[Journal Article] Glyoxalase I reduces glycative and oxidative stress and prevents age-related endothelial dysfunction through modulation of endothelial nitric oxide synthase phosphorylation.2014
Author(s)
Jo-Watanabe A, Ohse T, Nishimatsu H, Takahashi M, Ikeda Y, Wada T, Shirakawa J, Nagai R, Miyata T, Nagano T, Hirata Y, Inagi R, Nangaku M.
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Journal Title
Aging Cell
Volume: Epub ahead of print
Issue: 3
Pages: 519-28
DOI
Related Report
Peer Reviewed / Open Access
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