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Can beneficial effects of food factors reach embryo via mother's body?

Research Project

Project/Area Number 24650492
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeSingle-year Grants
Research Field Eating habits, studies on eating habits
Research InstitutionUniversity of Miyazaki

Principal Investigator

SAKAKIBARA HIROYUKI  宮崎大学, 農学部, 准教授 (20403701)

Co-Investigator(Kenkyū-buntansha) SHIMOI Kayoko  静岡県立大学, 環境科学研究所, 教授 (10162728)
Project Period (FY) 2012-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords抗酸化成分 / 母子間移行 / 胎児益性 / 食品機能 / 脂質代謝 / 次世代健康影響 / アントシアニン
Research Abstract

We evaluated whether beneficial effects existed in the foods and food factors can reach embryo and infant via mother's body, and obtained the results indicating that some factors, such as bilberry anthocyanins, might affect on the lipid metabolic pathway, but not the antioxidative system, in the liver on embryo, when mothers were consuming food factors. On the other hand, extracts of bitter cucumber, which has been reported to reduce the hepatic triacylglycerol level in the adult animals, did not exert any effects on hepatic lipid metabolism in the mice embryo. We are continuing the studies to obtain further evidences on this research topics.

Report

(3 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • Research Products

    (4 results)

All 2013 Other

All Presentation (4 results) (of which Invited: 1 results)

  • [Presentation] 母体が摂取したビルベリーアントシアニンの胎児移行性2013

    • Author(s)
      吉武稔貴、窄野昌信、下位香代子、榊原啓之
    • Organizer
      第18回日本フードファクター学会学術集会
    • Place of Presentation
      東京農業大学(東京)
    • Year and Date
      2013-11-09
    • Related Report
      2013 Final Research Report
  • [Presentation] 機能性食品研究に携わって17年目の挑戦-食品成分と体内リズムのクロノコミュニケーション-2013

    • Author(s)
      榊原啓之
    • Organizer
      金沢和樹先生退職記念講演会-食品・医薬品研究の最前線
    • Place of Presentation
      ANAクラウンホテル(神戸)
    • Year and Date
      2013-03-16
    • Related Report
      2013 Final Research Report
  • [Presentation] 母体が摂取したビルベリーアントシアニンの胎児移行性

    • Author(s)
      吉武稔貴、窄野昌信、下位香代子、榊原啓之
    • Organizer
      第18回日本フードファクター学会学術集会
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
  • [Presentation] 機能性食品研究に携わって17年目の挑戦-食品成分と体内リズムのクロノコミュニケーション-

    • Author(s)
      榊原啓之
    • Organizer
      金沢和樹先生退職記念講演会-食品・医薬品研究の最前線
    • Place of Presentation
      ANAクラウンホテル、神戸
    • Related Report
      2012 Research-status Report
    • Invited

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Published: 2013-05-31   Modified: 2019-07-29  

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