| Project/Area Number |
24650499
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Eating habits, studies on eating habits
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| Research Institution | Shokei Gakuin College |
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Principal Investigator |
Hoshi Seiko 尚絅学院大学, 総合人間科学部, 教授 (30564968)
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2012: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Keywords | カルシウム不足 / 内臓脂肪 / 脂質代謝異常 / メタボリックシンドローム / 肝臓脂質 / 肥満 / ラット / 栄養学 / 成長期 / カルシウム / 乳たんぱく質 / 骨 / 脂質代謝 / 生活習慣病 / ｶﾙｼｳﾑ / 幼児期 |
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| Outline of Final Research Achievements |
It was studied the effect on the lipid metabolism of the rats fed a low-Ca diet. In growth period, Ca deficiency inhibited significantly growth such as reduction of bone mass and loss of lean body mass. Then, plasma free fatty acid concentration was increased, lipid accumulation in the liver was induced.
In Japan, since the school age to consume milk in school meals, Ca intake has been relatively satisfied. However, Ca intake is drastically reduced for not eating school meals after the 15-year-old. Such a model the Ca intake situation of Japan was experiment. Rats in the growth phase had eaten a standard Ca diet, were given a low-Ca- high lipid energy diet after growth. Calcium deficiency of later growth was studied the effect on lipid metabolism. By the lack of Ca intake, the negative effect on the lipid metabolism were observed such as increased amount of visceral fat, rise in fasting plasma TG concentration, liver lipid accumulation and reduction of HDL cholesterol concentration.
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