| Project/Area Number |
24651136
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Nanomaterials/Nanobioscience
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| Research Institution | Kyoto University |
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Principal Investigator |
CHEN Yong 京都大学, 物質-細胞統合システム拠点, 教授 (70512458)
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| Co-Investigator(Kenkyū-buntansha) |
LI Liu 京都大学, 物質-細胞統合システム拠点, 助教 (50380093)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 3次元 / スカフォード / ヒト多能性幹細胞 / フィーダーフリ / ３次元 |
|---|
| Research Abstract |
Human pluripotent stem cells (hPSCs) are useful resources fortissue engineering, drug screening, and regenerative medicine. Cellular microenvironmental cues play critical roles in regulating hPSCs functions, but it is challenging to control them with synthetic components. In this project, we focus to develop a 3D nano-lattices scaffold for maintaining pluripotent stem cell culture based on micro-engineering tools and techniques. hPSCs on 3D nano-lattics scaffold showed a growth rate and they retained their pluripotency.
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