Chromatin loop structure prediction via fatgraph
Project/Area Number |
24651225
|
Research Category |
Grant-in-Aid for Challenging Exploratory Research
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Allocation Type | Multi-year Fund |
Research Field |
System genome science
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Research Institution | The University of Tokyo |
Principal Investigator |
KODAMA Hiroki 東京大学, 数理(科)学研究科(研究院), 特任准教授 (40466826)
|
Co-Investigator(Kenkyū-buntansha) |
IHARA Shigeo 東京大学, 先端科学技術研究センター, 教授 (30345136)
|
Project Period (FY) |
2012-04-01 – 2015-03-31
|
Project Status |
Completed (Fiscal Year 2014)
|
Budget Amount *help |
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
|
Keywords | トポロジー / SO(3)-接続 / ファットグラフ / 生命生体情報学 / 国際研究者交流(オーストリア) / 国際研究者交流(デンマーク) / タンパク質 / カントール集合 / 蛋白質 / 核酸 / 国際情報交換(デンマーク) / 国際研究者交流(オーストリア) / 国際研究者交流(デンマーク) |
Outline of Final Research Achievements |
SO(3)-connection model of protein is a graph that each vertex is a peptide unit and on each edge rotation matrix of peptide units is given. We used this model to construct a system that visualize the difference of 3D structures of proteins. We contrived a model via Cantor set that explicates the loop structure of Chromatin. We also described pH-induced protein denaturation via grid model of protein.
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Report
(4 results)
Research Products
(3 results)