Dynamics of artificial self-supported lipid membranes
| Project/Area Number |
24655056
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Analytical chemistry
|
|---|
| Research Institution | Chiba University |
|---|
Principal Investigator |
FUJINAMI Masanori 千葉大学, 工学(系)研究科(研究院), 教授 (50311436)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
TOYOTA Taro 東京大学, 大学院総合文化研究科, 准教授 (80422377)
NOMOTO Tomonori 千葉大学, 大学院工学研究科, 助教 (00510520)
|
|---|
| Project Period (FY) |
2012-04-01 – 2014-03-31
|
| Project Status |
Completed (Fiscal Year 2013)
|
| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
|
|---|
| Keywords | 膜張力 / 脂質二分子膜 / レーザー誘起界面変形分光法 / 光学顕微鏡 / コレステロール / 脂質分子 / 脂質膜 / 界面張力 / レーザー分光 / 膜ゆらぎ / レーザー誘起界面変形分光 |
|---|
| Research Abstract |
In this study, we have developed a methodology of detecting interfacial tension and related properties of a planar artificial self-supported lipid membrane, or black lipid membrane (BLM) for studying fluctuations and mechanical/chemical properties of biomembranes. Laser-induced surface deformation spectroscopy was applied by optimizing the refractive indices of two water phases. As a result, measurement of fluctuation and interfacial tension of BLM has been succeeded and their dependence on its compositions and molecular was discussed.
|
Report
(3 results)
Research Products
(21 results)
-
-
-
[Journal Article] Near-infrared-fluorescence imaging of lymph nodes by using liposomally formulated indocyanine green derivatives2014
Author(s)
Taro Toyota, Hiromichi Fujito, Akiko Suganami, Tomoki Ouchi, Aki Ooishi, Akira Aoki, Kazutaka Onoue, Yutaka Muraki, Tomoyuki Madono, Masanori Fujinami, Yutaka Tamura, Hideki Hayashi
-
Journal Title
Bioorganic & Medical Chemistry
Volume: 22
Issue: 2
Pages: 721-727
DOI
Related Report
Peer Reviewed / Open Access
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
