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Measurement of Molecular Weight by Shockwave and Developement of Mass-shift Method

Research Project

Project/Area Number 24655063
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Analytical chemistry
Research InstitutionKyoto Institute of Technology

Principal Investigator

ICHINOSE Nobuyuki  京都工芸繊維大学, 工芸科学研究科, 教授 (00232405)

Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywordsレーザー衝撃波 / 分子量測定 / 分子形状 / 生体高分子 / 会合体 / レーザー誘起衝撃波 / 多糖類 / ナノ粒子
Outline of Final Research Achievements

Measurement of molecular weight of polymers from the microscopic distance of movement, which is afforded by the action of laser-induced shockwave, has been studied. The distances afforded to polysaccharides and proteins incresed with the molecular weight in different manners and association like dimerization of molecules showed a shift in the distance corresponding to their molecular weight. A decrease of the distance was observed when proteins were associated with surfactant molecules although the molecular weights were expected to increase. This has been attributed to a change in their molecular shape which was elongated by the association of the surfactant molecules. It has been concluded from these results that molecular shape in solution is an important factor as well as molecular weight determine the distance afforded by the action of shockwave in solution.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (2 results)

All 2015

All Presentation (2 results)

  • [Presentation] 多糖類高分子のレーザー衝撃波クロマトグラフィー2015

    • Author(s)
      一ノ瀬暢之・岡田光暁・永原哲彦
    • Organizer
      2015年光化学討論会
    • Place of Presentation
      大阪市立大学
    • Year and Date
      2015-09-11 – 2015-09-13
    • Related Report
      2014 Annual Research Report
  • [Presentation] レーザー衝撃波によるタンパクの液中移動に対する界面活性剤の添加効果2015

    • Author(s)
      一ノ瀬暢之・芝原慶・永原哲彦
    • Organizer
      2015年光化学討論会
    • Place of Presentation
      大阪市立大学
    • Year and Date
      2015-09-11 – 2015-09-13
    • Related Report
      2014 Annual Research Report

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Published: 2013-05-31   Modified: 2019-07-29  

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