Design and in vitro evaluation method for biomedical titanium implant materials using a spatial gap
| Project/Area Number |
24656386
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Inorganic materials/Physical properties
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| Research Institution | Okayama University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
OSAKA Akiyoshi 岡山大学, 大学院自然科学研究科, 教授 (20033409)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 酸化チタン / アパタイト / 擬似体液 / 動的環境 / フローリアクター / 空間デザイン / 隙間空間 |
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| Research Abstract |
A recently developed "GRAPE technology" provides titanium or titanium alloy implants with spontaneous apatite-forming ability in vitro, which requires properly designed gaps and optimum heat treatment in air. We developed a new flow reactor system of a simulated body fluid combined with a spatial gap consisting of parallel-aligned two pieces of thermally-oxidized titanium substrates to examine in vitro apatite deposition behaviors in the spatial gap. The mechanism of in vitro apatite formation on the thermally-oxidized titanium substrate that parallel-aligned to another titanium-alloy substrate with optimized 0.5-mm gap width was proposed in order to establish design concept for a new implant device using a spatial gap.
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Report
(3 results)
Research Products
(4 results)
